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| FSummaryGene Symbol: F Description: fusion protein Species: nipah virus Publications Nipah virus: a recently emergent deadly paramyxovirusK B Chua Department of Medical Microbiology, University of Malaya Medical Center, 50603 Kuala Lumpur, Malaysia Science 288:1432-5 Molecular characterization of Nipah virus, a newly emergent paramyxovirusB H Harcourt Respiratory and Enteric Viruses Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA Virology 271:334-49 Molecular characterization of the polymerase gene and genomic termini of Nipah virusB H Harcourt Respiratory and Enteric Viruses Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA Virology 287:192-201 Complete nucleotide sequences of Nipah virus isolates from MalaysiaY P Chan Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia J Gen Virol 82:2151-5 Crystallization and preliminary crystallographic analysis of the fusion core from two new zoonotic paramyxoviruses, Nipah virus and Hendra virusYanhui Xu Laboratory of Structural Biology and MOE Laboratory of Protein Sciences, School of Life Sciences and Bio Engineering, Tsinghua University, Beijing 100084, People s Republic of China Acta Crystallogr D Biol Crystallogr 60:1161-4 Isolation and molecular identification of Nipah virus from pigsSazaly AbuBakar University of Malaya, Kuala Lumpur, Malaysia Emerg Infect Dis 10:2228-30 Endocytosis of the Nipah virus glycoproteinsCarola Vogt Institut für Virologie, Philipps University of Marburg, Germany J Virol 79:3865-72 N-glycans on Nipah virus fusion protein protect against neutralization but reduce membrane fusion and viral entryHector C Aguilar Department of MIMG, David Geffen Schoo of Medicine at UCLA, Los Angeles, CA 90095, USA J Virol 80:4878-89 Polybasic KKR motif in the cytoplasmic tail of Nipah virus fusion protein modulates membrane fusion by inside-out signalingHector C Aguilar Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine, University of California at Los Angeles, 609 Charles E Young Drive East, Los Angeles, CA 90095, USA J Virol 81:4520-32 | Scientific Experts
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Publications
Nipah virus: a recently emergent deadly paramyxovirusK B Chua
Department of Medical Microbiology, University of Malaya Medical Center, 50603 Kuala Lumpur, Malaysia
Science 288:1432-5
Department of Medical Microbiology, University of Malaya Medical Center, 50603 Kuala Lumpur, Malaysia
Science 288:1432-5
..Like Hendra virus, Nipah virus is unusual among the paramyxoviruses in its ability to infect and cause potentially fatal disease in a number of host species, including humans...
Molecular characterization of Nipah virus, a newly emergent paramyxovirusB H Harcourt
Respiratory and Enteric Viruses Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Virology 271:334-49
Respiratory and Enteric Viruses Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Virology 271:334-49
..We generated the sequences of the N, P/C/V, M, F, and G genes of NV and compared these sequences with those of HV and other members of the family Paramyxoviridae...
Molecular characterization of the polymerase gene and genomic termini of Nipah virusB H Harcourt
Respiratory and Enteric Viruses Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Virology 287:192-201
Respiratory and Enteric Viruses Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
Virology 287:192-201
..The comparison of the structures of the genomes of HV and NV is now complete and this information will help to establish the taxonomic position of these novel viruses within the family Paramyxoviridae...
Complete nucleotide sequences of Nipah virus isolates from MalaysiaY P Chan
Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia
J Gen Virol 82:2151-5
Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia
J Gen Virol 82:2151-5
....
Crystallization and preliminary crystallographic analysis of the fusion core from two new zoonotic paramyxoviruses, Nipah virus and Hendra virusYanhui Xu
Laboratory of Structural Biology and MOE Laboratory of Protein Sciences, School of Life Sciences and Bio Engineering, Tsinghua University, Beijing 100084, People s Republic of China
Acta Crystallogr D Biol Crystallogr 60:1161-4
Laboratory of Structural Biology and MOE Laboratory of Protein Sciences, School of Life Sciences and Bio Engineering, Tsinghua University, Beijing 100084, People s Republic of China
Acta Crystallogr D Biol Crystallogr 60:1161-4
Highly conserved heptad-repeat (HR1 and HR2) regions in class I viral fusion (F) proteins, including the F protein from paramyxovirus, interact with each other post-fusion to form a six-helix bundle called a fusion core...
Isolation and molecular identification of Nipah virus from pigsSazaly AbuBakar
University of Malaya, Kuala Lumpur, Malaysia
Emerg Infect Dis 10:2228-30
University of Malaya, Kuala Lumpur, Malaysia
Emerg Infect Dis 10:2228-30
..At least two different Nipah virus strains, including a previously unreported strain, were identified. The findings highlight the possibility that the Malaysia outbreaks had two origins of Nipah virus infections...
Endocytosis of the Nipah virus glycoproteinsCarola Vogt
Institut für Virologie, Philipps University of Marburg, Germany
J Virol 79:3865-72
Institut für Virologie, Philipps University of Marburg, Germany
J Virol 79:3865-72
Nipah virus (NiV), a highly pathogenic member of the family Paramyxoviridae, encodes the surface glycoproteins F and G...
N-glycans on Nipah virus fusion protein protect against neutralization but reduce membrane fusion and viral entryHector C Aguilar
Department of MIMG, David Geffen Schoo of Medicine at UCLA, Los Angeles, CA 90095, USA
J Virol 80:4878-89
Department of MIMG, David Geffen Schoo of Medicine at UCLA, Los Angeles, CA 90095, USA
J Virol 80:4878-89
Nipah virus (NiV) is a deadly emerging paramyxovirus. The NiV attachment (NiV-G) and fusion (NiV-F) envelope glycoproteins mediate both syncytium formation and viral entry...
Polybasic KKR motif in the cytoplasmic tail of Nipah virus fusion protein modulates membrane fusion by inside-out signalingHector C Aguilar
Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine, University of California at Los Angeles, 609 Charles E Young Drive East, Los Angeles, CA 90095, USA
J Virol 81:4520-32
Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine, University of California at Los Angeles, 609 Charles E Young Drive East, Los Angeles, CA 90095, USA
J Virol 81:4520-32
..Here we report that specific residues in the cytoplasmic tail of the Nipah virus fusion protein (NiV-F) modulate its fusogenic activity. Truncation of the cytoplasmic tail of NiV-F greatly inhibited cell-cell fusion...