Gene Symbol: hrp1
Description: hypoxic response protein
Species: Mycobacterium tuberculosis H37Rv

Top Publications

  1. Sun C, Yang G, Yuan J, Peng X, Zhang C, Zhai X, et al. Mycobacterium tuberculosis hypoxic response protein 1 (Hrp1) augments the pro-inflammatory response and enhances the survival of Mycobacterium smegmatis in murine macrophages. J Med Microbiol. 2017;66:1033-1044 pubmed publisher
    ..M. tuberculosis protein Rv2626c plays a significant role in stimulating macrophages to provoke a pro-inflammatory response and in mycobacterial survival during infection. ..
  2. Bashir N, Kounsar F, Mukhopadhyay S, Hasnain S. Mycobacterium tuberculosis conserved hypothetical protein rRv2626c modulates macrophage effector functions. Immunology. 2010;130:34-45 pubmed publisher
    ..Rv2626c therefore appears to modulate macrophage effector functions by eliciting both innate and adaptive immune responses, suggesting its possible use as a vaccine candidate...
  3. Vasilevsky S, Stojanov M, Greub G, Baud D. Chlamydial polymorphic membrane proteins: regulation, function and potential vaccine candidates. Virulence. 2016;7:11-22 pubmed publisher
    ..Thus, Pmps might be important not only for the pathogenesis of chlamydial infection, but also as potential candidate vaccine proteins. ..