Gene Symbol: groES
Description: chaperonin GroES
Alias: cpn10, mpt57
Species: Mycobacterium tuberculosis H37Rv
Barnes P, Mehra V, Rivoire B, Fong S, Brennan P, Voegtline M, et al
. Immunoreactivity of a 10-kDa antigen of Mycobacterium tuberculosis. J Immunol. 1992;148:1835-40 pubmed
..Our findings indicate that the 10-kDa Ag of M. tuberculosis is highly immunoreactive and should be evaluated for its capacity to elicit protective immunity. ..
Kong T, Coates A, Butcher P, Hickman C, Shinnick T. Mycobacterium tuberculosis expresses two chaperonin-60 homologs. Proc Natl Acad Sci U S A. 1993;90:2608-12 pubmed
..The 10-kDa antigen has homology with the GroES or chaperonin-10 family of heat shock proteins. These two proteins are encoded by separate genes in M...
Maurya V, Singh K, Sinha S. Suppression of Eis and expression of Wag31 and GroES in Mycobacterium tuberculosis cytosol under anaerobic culture conditions. Indian J Exp Biol. 2014;52:773-80 pubmed
..On the other hand, 4 proteins were highly expressed, with two of them (Wag31 and GroES) being uniquely expressed under anaerobic conditions...
Baird P, Hall L, Coates A. Cloning and sequence analysis of the 10 kDa antigen gene of Mycobacterium tuberculosis. J Gen Microbiol. 1989;135:931-9 pubmed
..A hairpin loop identified in the upstream sequence may also be important in regulation of the gene. ..
Shinnick T, Plikaytis B, Hyche A, Van Landingham R, Walker L. The Mycobacterium tuberculosis BCG-a protein has homology with the Escherichia coli GroES protein. Nucleic Acids Res. 1989;17:1254 pubmed
Baird P, Hall L, Coates A. A major antigen from Mycobacterium tuberculosis which is homologous to the heat shock proteins groES from E. coli and the htpA gene product of Coxiella burneti. Nucleic Acids Res. 1988;16:9047 pubmed
Vijayakrishnan S, Qamra R, Verma C, Sen R, Mande S. Cation-mediated interplay of loops in chaperonin-10. J Biomol Struct Dyn. 2006;23:365-76 pubmed
..The divalent metal ions may thus act as key elements in the protein folding cycle, and trigger a conformational switch for molecular recognition. ..