espB

Summary

Gene Symbol: espB
Description: ESX-1 secretion-associated protein EspB
Species: Mycobacterium tuberculosis H37Rv

Top Publications

  1. Lodes M, Dillon D, Mohamath R, Day C, Benson D, Reynolds L, et al. Serological expression cloning and immunological evaluation of MTB48, a novel Mycobacterium tuberculosis antigen. J Clin Microbiol. 2001;39:2485-93 pubmed
    ..tuberculosis infection when it is combined with other known immunodominant antigens, such as the 38-kDa antigen. ..
  2. Huang D, Bao L. Mycobacterium tuberculosis EspB protein suppresses interferon-γ-induced autophagy in murine macrophages. J Microbiol Immunol Infect. 2016;49:859-865 pubmed publisher
    ..Although the early secretory antigenic target 6 (ESAT-6) system 1 (ESX-1) secretion-associated protein B (EspB) of Mtb is strongly linked to immunogenicity and virulence of this organism, its mechanism of action remains ..
  3. Korotkova N, Piton J, Wagner J, Boy Röttger S, Japaridze A, Evans T, et al. Structure of EspB, a secreted substrate of the ESX-1 secretion system of Mycobacterium tuberculosis. J Struct Biol. 2015;191:236-44 pubmed publisher
    ..tuberculosis. ESX-1 secreted protein B (EspB) contains putative PE (Pro-Glu) and PPE (Pro-Pro-Glu) domains, and a C-terminal domain, which is processed by MycP1 ..
  4. McLaughlin B, Chon J, MacGurn J, Carlsson F, Cheng T, Cox J, et al. A mycobacterium ESX-1-secreted virulence factor with unique requirements for export. PLoS Pathog. 2007;3:e105 pubmed
    ..We have renamed the Rv3881c/Mh3881c gene espB for ESX-1 substrate protein B. Secretion of M...