eccD1

Summary

Gene Symbol: eccD1
Description: ESX-1 secretion system protein EccD1
Alias: snm4
Species: Mycobacterium tuberculosis H37Rv

Top Publications

  1. Wagner J, Chan S, Evans T, Kahng S, Kim J, Arbing M, et al. Structures of EccB1 and EccD1 from the core complex of the mycobacterial ESX-1 type VII secretion system. BMC Struct Biol. 2016;16:5 pubmed publisher
    ..This study characterizes the structures of the soluble domains of two conserved core ESX-1 components - EccB1 and EccD1. The periplasmic domain of EccB1 consists of 4 repeat domains and a central domain, which together form a quasi 2-..
  2. McLaughlin B, Chon J, MacGurn J, Carlsson F, Cheng T, Cox J, et al. A mycobacterium ESX-1-secreted virulence factor with unique requirements for export. PLoS Pathog. 2007;3:e105 pubmed
    ..The results establish EspB as a substrate of ESX-1 that is required for virulence and growth in macrophages and suggests that the contribution of ESX-1 to virulence may arise from the secretion of multiple independent substrates. ..