eccCb1

Summary

Gene Symbol: eccCb1
Description: ESX-1 secretion system protein EccCb
Alias: snm2
Species: Mycobacterium tuberculosis H37Rv

Top Publications

  1. Bao Y, Qi Z, Bao L. [Cloning, expression and bioinformatic analysis of Rv3871 gene related to Mycobacterium tuberculosis virulent protein secretion]. Nan Fang Yi Ke Da Xue Xue Bao. 2009;29:2371-4 pubmed
    ..The structural and functional differences of the gene between pathogenic and non-pathogenic mycobacteria identified by bioinformatics provide some evidence for the pathogenesis and drug targets of tuberculosis. ..
  2. Refaya A, Sivakumar S, Sundararaman B, Narayanan S. Polymorphism in the RD1 locus and its effect on downstream genes among South Indian clinical isolates of Mycobacterium tuberculosis. J Med Microbiol. 2012;61:1352-9 pubmed publisher
    ..These data suggest that changes in transcription levels resulting from insertion of different copy numbers of the repeat element may affect regulation of gene expression in M. tuberculosis. ..
  3. McLaughlin B, Chon J, MacGurn J, Carlsson F, Cheng T, Cox J, et al. A mycobacterium ESX-1-secreted virulence factor with unique requirements for export. PLoS Pathog. 2007;3:e105 pubmed
    ..The results establish EspB as a substrate of ESX-1 that is required for virulence and growth in macrophages and suggests that the contribution of ESX-1 to virulence may arise from the secretion of multiple independent substrates. ..