deoD

Summary

Gene Symbol: deoD
Description: purine nucleoside phosphorylase
Species: Mycobacterium bovis AF2122/97

Top Publications

  1. ncbi Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces
    W Shi
    Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA
    Biochemistry 40:8204-15. 2001
  2. ncbi Over-the-barrier transition state analogues and crystal structure with Mycobacterium tuberculosis purine nucleoside phosphorylase
    Andrzej Lewandowicz
    Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA
    Biochemistry 42:6057-66. 2003

Detail Information

Publications2

  1. ncbi Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces
    W Shi
    Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA
    Biochemistry 40:8204-15. 2001
    ..Loose packing of the pieces of ImmH in the catalytic site establishes that covalent connectivity in ImmH is required to achieve the tightly bound complex...
  2. ncbi Over-the-barrier transition state analogues and crystal structure with Mycobacterium tuberculosis purine nucleoside phosphorylase
    Andrzej Lewandowicz
    Department of Biochemistry, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, New York 10461, USA
    Biochemistry 42:6057-66. 2003
    ..This approach has resulted in the highest affinity transition state analogues known for MtPNP...