Zfp161

Summary

Gene Symbol: Zfp161
Description: zinc finger protein 161
Alias: ZF5, zfp-161, zinc finger protein 5
Species: mouse

Top Publications

  1. ncbi Transcriptional repressor ZF5 identifies a new conserved domain in zinc finger proteins
    M Numoto
    Research Institute for Nuclear Medicine and Biology, Hiroshima University, Japan
    Nucleic Acids Res 21:3767-75. 1993
  2. ncbi Expression cloning and intracellular localization of a human ZF5 homologue
    K Sugiura
    Department of Anatomy, Nagoya University School of Medicine, Showa Ku, Japan
    Biochim Biophys Acta 1352:23-6. 1997
  3. ncbi The human gene ZFP161 on 18p11.21-pter encodes a putative c-myc repressor and is homologous to murine Zfp161 (Chr 17) and Zfp161-rs1 (X Chr)
    I Sobek-Klocke
    Faculty of Biology, Genetechnology Microbiology Unit, University of Bielefeld, Germany
    Genomics 43:156-64. 1997
  4. ncbi Genomic cloning and characterization of the mouse POZ/zinc-finger protein ZF5
    K Yokoro
    Department of Dermatology, Hiroshima University School of Medicine, Japan
    Biochem Biophys Res Commun 246:668-74. 1998
  5. ncbi Analysis of the consensus binding sequence and the DNA-binding domain of ZF5
    T Obata
    Department of Dermatology, Hiroshima University School of Medicine, Japan
    Biochem Biophys Res Commun 255:528-34. 1999
  6. ncbi Biochemical and genetic evidence for a role of IGHMBP2 in the translational machinery
    Mariangels De Planell-Saguer
    Department of Pathology and Laboratory Medicine, Division of Neuropathology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6100, USA
    Hum Mol Genet 18:2115-26. 2009

Scientific Experts

  • T Obata
  • Mariangels De Planell-Saguer
  • Zissimos Mourelatos
  • Gregory A Cox
  • Maria Celina Rodicio
  • David G Schroeder
  • K Yokoro
  • I Sobek-Klocke
  • M Numoto
  • K Sugiura
  • A Yanagidani
  • S Yamamoto
  • U Eichenlaub-Ritter
  • Y Muro
  • K Rojas
  • H Jockusch
  • J Overhauser
  • M Ohashi
  • R Klocke
  • C Disqué-Kochem
  • T Kamimoto
  • T Wakabayashi
  • H Ponstingl
  • M Hagiwara
  • Y Nagai
  • A Breuning
  • M Ronsiek
  • K Merrell
  • K Calame
  • K Yanagihara
  • J Kaplan
  • K K Wong
  • K Kamiya
  • O Niwa

Detail Information

Publications6

  1. ncbi Transcriptional repressor ZF5 identifies a new conserved domain in zinc finger proteins
    M Numoto
    Research Institute for Nuclear Medicine and Biology, Hiroshima University, Japan
    Nucleic Acids Res 21:3767-75. 1993
    We have cloned a cDNA encoding a new murine C2H2 zinc finger protein, ZF5. The 51.3 kD protein contains five GL1-Kruppel type zinc fingers at the C-terminus...
  2. ncbi Expression cloning and intracellular localization of a human ZF5 homologue
    K Sugiura
    Department of Anatomy, Nagoya University School of Medicine, Showa Ku, Japan
    Biochim Biophys Acta 1352:23-6. 1997
    We isolated a cDNA encoding a human homologue of ZF5 (hZF5), which has five Kruppel-like C2H2 type zinc fingers at carboxyl terminus and the BTB/POZ (poxvirus and zinc finger) at the amino terminus, using autoimmune sera from a patient ..
  3. ncbi The human gene ZFP161 on 18p11.21-pter encodes a putative c-myc repressor and is homologous to murine Zfp161 (Chr 17) and Zfp161-rs1 (X Chr)
    I Sobek-Klocke
    Faculty of Biology, Genetechnology Microbiology Unit, University of Bielefeld, Germany
    Genomics 43:156-64. 1997
    ..The cDNA of the gene termed ZFP161 has an open reading frame of 1347 bp...
  4. ncbi Genomic cloning and characterization of the mouse POZ/zinc-finger protein ZF5
    K Yokoro
    Department of Dermatology, Hiroshima University School of Medicine, Japan
    Biochem Biophys Res Commun 246:668-74. 1998
    We isolated genomic DNA containing the entire sequence of ZF5, which was originally identified by its ability to repress the mouse c-myc promoter and which was characterized as one of the POZ (Poxvirus and zinc finger) proteins...
  5. ncbi Analysis of the consensus binding sequence and the DNA-binding domain of ZF5
    T Obata
    Department of Dermatology, Hiroshima University School of Medicine, Japan
    Biochem Biophys Res Commun 255:528-34. 1999
    Murine ZF5 is a transcription factor with five zinc finger motifs that represses the c-myc gene by binding to two GC-rich elements at the promoter region...
  6. ncbi Biochemical and genetic evidence for a role of IGHMBP2 in the translational machinery
    Mariangels De Planell-Saguer
    Department of Pathology and Laboratory Medicine, Division of Neuropathology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6100, USA
    Hum Mol Genet 18:2115-26. 2009
    ..Our findings strongly suggest that IGHMBP2 is a component of the translational machinery and that these components can be manipulated genetically to suppress motor neuron degeneration...