Wdr45

Summary

Gene Symbol: Wdr45
Description: WD repeat domain 45
Alias: C79260, DXImx38e, JM5, Sfc19, WIPI-4, Wdrx1, WD repeat domain phosphoinositide-interacting protein 4, WD repeat domain, X-linked 1, WD repeat-containing protein 45
Species: mouse
Products:     Wdr45

Top Publications

  1. Brunkow M, Jeffery E, Hjerrild K, Paeper B, Clark L, Yasayko S, et al. Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse. Nat Genet. 2001;27:68-73 pubmed
    ..In sf mice, a frameshift mutation results in a product lacking the forkhead domain. Genetic complementation demonstrates that the protein product of Foxp3, scurfin, is essential for normal immune homeostasis. ..
  2. Zhao Y, Sun L, Miao G, Ji C, Zhao H, Sun H, et al. The autophagy gene Wdr45/Wipi4 regulates learning and memory function and axonal homeostasis. Autophagy. 2015;11:881-90 pubmed publisher
    b>WDR45/WIPI4, encoding a WD40 repeat-containing PtdIns(3)P binding protein, is essential for the basal autophagy pathway...

Scientific Experts