Genomes and Genes
Gene Symbol: Vrk1
Description: vaccinia related kinase 1
Alias: 51PK, serine/threonine-protein kinase VRK1, serine/threonine-protein kinase 51PK
- Park C, Choi B, Jeong M, Kim S, Kim W, Song Y, et al. Protein kinase C? regulates vaccinia-related kinase 1 in DNA damage-induced apoptosis. Mol Biol Cell. 2011;22:1398-408 pubmed publisherVaccinia-related kinase 1 (VRK1) is a novel serine/threonine kinase that plays an important role in cell proliferation. However, little is known about the upstream regulators of VRK1 activity...
- Quiel A, Jürgen B, Greinacher A, Lassen S, Wörl R, Witt S, et al. Sensitive detection of idiotypic platelet-reactive alloantibodies by an electrical protein chip. Biosens Bioelectron. 2012;36:207-11 pubmed publisher..With this electrical chip assay it is possible to detect antibodies against HPA-1a, HPA-5b and HLA with high sensitivity and specificity in less than half the duration of the MAIPA protocol with similar intra- and interassay variance. ..
- Choi Y, Lim J, Jeong M, Kim K. HnRNP A1 phosphorylated by VRK1 stimulates telomerase and its binding to telomeric DNA sequence. Nucleic Acids Res. 2012;40:8499-518 pubmed..Here, we identified hnRNP A1 as a novel substrate for vaccinia-related kinase 1 (VRK1), a cell cycle regulating kinase...
- Kim J, Choi Y, Chang S, Kim K, Je J. Defective folliculogenesis in female mice lacking Vaccinia-related kinase 1. Sci Rep. 2012;2:468 pubmed publisherThe Vaccinia-related kinase 1(VRK1), which is generally implicated in modulating cell cycle, plays important roles in mammalian gametogenesis...