Vps4a

Summary

Gene Symbol: Vps4a
Description: vacuolar protein sorting 4A
Alias: 4930589C15Rik, AI325971, AW553189, vacuolar protein sorting-associated protein 4A, vacuolar protein sorting protein 4a, vps4a
Species: mouse
Products:     Vps4a

Top Publications

  1. Beyer A, Scheuring S, Müller S, Mincheva A, Lichter P, Köhrer K. Comparative sequence and expression analyses of four mammalian VPS4 genes. Gene. 2003;305:47-59 pubmed
    ..databases from completely or partially sequenced organisms revealed the existence of up to three paralogues, VPS4a, -b, and -c...
  2. Silvestri L, Ruthel G, Kallstrom G, Warfield K, Swenson D, Nelle T, et al. Involvement of vacuolar protein sorting pathway in Ebola virus release independent of TSG101 interaction. J Infect Dis. 2007;196 Suppl 2:S264-70 pubmed
    ..These data show that EBOV can use vps proteins independently of TSG101 for budding and reveal VPS4 as a potential target for filovirus therapeutics. ..
  3. Sahu R, Kaushik S, Clement C, Cannizzo E, Scharf B, Follenzi A, et al. Microautophagy of cytosolic proteins by late endosomes. Dev Cell. 2011;20:131-9 pubmed publisher
    ..Therefore, we propose that endosomal microautophagy shares molecular components with both the endocytic and autophagic pathways. ..
  4. Iwaya N, Kuwahara Y, Fujiwara Y, Goda N, Tenno T, Akiyama K, et al. A common substrate recognition mode conserved between katanin p60 and VPS4 governs microtubule severing and membrane skeleton reorganization. J Biol Chem. 2010;285:16822-9 pubmed publisher
    ..A common mechanism is evolutionarily conserved between two distinct cellular events, one that drives microtubule severing and the other involving membrane skeletal reorganization. ..