Gene Symbol: Vmn2r81
Description: vomeronasal 2, receptor 81
Alias: EC1-V2R, EC1-VR2, V2rf2, vomeronasal 2, receptor 81, EC1-V2R pheromone receptor
Species: mouse
Products:     Vmn2r81

Top Publications

  1. Loconto J, Papes F, Chang E, Stowers L, Jones E, Takada T, et al. Functional expression of murine V2R pheromone receptors involves selective association with the M10 and M1 families of MHC class Ib molecules. Cell. 2003;112:607-18 pubmed
    ..The functional characterization of M10 highlights an unexpected role for MHC molecules in pheromone detection by mammalian VNO neurons. ..
  2. Ishii T, Mombaerts P. Expression of nonclassical class I major histocompatibility genes defines a tripartite organization of the mouse vomeronasal system. J Neurosci. 2008;28:2332-41 pubmed publisher
    ..Our results reveal a tripartite organization of the VNO and AOB, question the generality of the requirement of these nine H2-Mv molecules for V2R surface expression, and suggest that H2-Mvs can function in both dendrites and axons. ..
  3. Ishii T, Mombaerts P. Coordinated coexpression of two vomeronasal receptor V2R genes per neuron in the mouse. Mol Cell Neurosci. 2011;46:397-408 pubmed publisher
    ..Here, we describe two novel mouse strains with targeted mutations in the family-ABD V2R gene V2rf2 that begin to provide insight into this problem...
  4. Leinders Zufall T, Ishii T, Chamero P, Hendrix P, Oboti L, Schmid A, et al. A family of nonclassical class I MHC genes contributes to ultrasensitive chemodetection by mouse vomeronasal sensory neurons. J Neurosci. 2014;34:5121-33 pubmed publisher
    ..This physiological phenotype is displayed at the single-cell level and is cell autonomous: single V2rf2-expressing VSNs, which normally coexpress H2-Mv genes, display a decreased sensitivity to a peptide ligand in ?..
  5. Henion T, Madany P, Faden A, Schwarting G. ?3GnT2 null mice exhibit defective accessory olfactory bulb innervation. Mol Cell Neurosci. 2013;52:73-86 pubmed publisher
    ..These results identify a novel function for ?3GnT2 glycosylation in maintaining expression of layer-specific vomeronasal receptors, as well as adhesion molecules required for proper AOB glomerular formation. ..