Gene Symbol: Uqcrb
Description: ubiquinol-cytochrome c reductase binding protein
Alias: 2210415M14Rik, QP-C, QPC, UQBC, UQBP, UQPC, cytochrome b-c1 complex subunit 7, complex III subunit 7, complex III subunit VII, ubiquinol-cytochrome c reductase complex 14 kDa protein
Species: mouse
Products:     Uqcrb

Top Publications

  1. Schilling B, Murray J, Yoo C, Row R, Cusack M, Capaldi R, et al. Proteomic analysis of succinate dehydrogenase and ubiquinol-cytochrome c reductase (Complex II and III) isolated by immunoprecipitation from bovine and mouse heart mitochondria. Biochim Biophys Acta. 2006;1762:213-22 pubmed
    ..The identification of several posttranslational modifications, including the covalent FAD modification of flavoprotein subunit 1 from Complex II, was possible due to high mass spectrometric sequence coverage. ..
  2. Sadakata T, Furuichi T. Identification and mRNA expression of Ogdh, QP-C, and two predicted genes in the postnatal mouse brain. Neurosci Lett. 2006;405:217-22 pubmed
    ..High mRNA levels of d1401/Ogdh were observed in the olfactory bulb, hippocampus, cerebellum, and pons, whereas those of d1501 were detected in the granule cells of the olfactory bulb, dentate gyrus, and cerebellum. ..
  3. Jung H, Shim J, Lee J, Song Y, Park K, Choi S, et al. Terpestacin inhibits tumor angiogenesis by targeting UQCRB of mitochondrial complex III and suppressing hypoxia-induced reactive oxygen species production and cellular oxygen sensing. J Biol Chem. 2010;285:11584-95 pubmed publisher
    ..4-kDa subunit (UQCRB) of mitochondrial Complex III, resulting in inhibition of hypoxia-induced reactive oxygen species generation...