Gene Symbol: Uqcr11
Description: ubiquinol-cytochrome c reductase, complex III subunit XI
Alias: 0710008D09Rik, AL022707, Uqcr, cytochrome b-c1 complex subunit 10, complex III subunit 10, complex III subunit XI, ubiquinol-cytochrome c reductase (6.4kD) subunit, ubiquinol-cytochrome c reductase complex 6.4 kDa protein, ubiquinol-cytochrome c reductase subunit
Species: mouse
Products:     Uqcr11

Top Publications

  1. Schilling B, Murray J, Yoo C, Row R, Cusack M, Capaldi R, et al. Proteomic analysis of succinate dehydrogenase and ubiquinol-cytochrome c reductase (Complex II and III) isolated by immunoprecipitation from bovine and mouse heart mitochondria. Biochim Biophys Acta. 2006;1762:213-22 pubmed
    ..The identification of several posttranslational modifications, including the covalent FAD modification of flavoprotein subunit 1 from Complex II, was possible due to high mass spectrometric sequence coverage. ..
  2. Xu F, Ackerley C, Maj M, Addis J, Levandovskiy V, Lee J, et al. Disruption of a mitochondrial RNA-binding protein gene results in decreased cytochrome b expression and a marked reduction in ubiquinol-cytochrome c reductase activity in mouse heart mitochondria. Biochem J. 2008;416:15-26 pubmed publisher
    ..This defines the site for PTCD2 action in mammalian mitochondria and suggests a possible role for dysfunction of this protein in the aetiology of heart failure...
  3. Doucet Beaupré H, Gilbert C, Profes M, Chabrat A, Pacelli C, Giguère N, et al. Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons. Proc Natl Acad Sci U S A. 2016;113:E4387-96 pubmed publisher
    ..These results reveal the key role of these transcription factors beyond the early developmental stages and provide mechanistic links between mitochondrial dysfunctions, ?-synuclein aggregation, and the survival of dopaminergic neurons. ..