Gene Symbol: Ube2v1
Description: ubiquitin-conjugating enzyme E2 variant 1
Alias: 0610011J09Rik, AI256840, CROC-1, CROC1, D7Bwg1382e, UEV-1, ubiquitin-conjugating enzyme E2 variant 1
Species: mouse
Products:     Ube2v1

Top Publications

  1. Long M. A new function evolved from gene fusion. Genome Res. 2000;10:1655-7 pubmed
  2. Thomson T, Lozano J, Loukili N, Carrio R, Serras F, Cormand B, et al. Fusion of the human gene for the polyubiquitination coeffector UEV1 with Kua, a newly identified gene. Genome Res. 2000;10:1743-56 pubmed
    ..Therefore, the addition of a Kua domain to UEV in the fused Kua-UEV protein confers new biological properties to this regulator of variant polyubiquitination. ..
  3. Jackson B, Daniel W. Recurrent carcinoma of the rectum, surgical treatment. Calif Med. 1959;91:149-50 pubmed
    ..Surgical procedures used in the treatment of the common types of recurrence are discussed. ..
  4. Petroski M, Zhou X, Dong G, Daniel Issakani S, Payan D, Huang J. Substrate modification with lysine 63-linked ubiquitin chains through the UBC13-UEV1A ubiquitin-conjugating enzyme. J Biol Chem. 2007;282:29936-45 pubmed
  5. Wu J, Chen Y, Lu L, Wu Y, Paulsen M, Ljungman M, et al. Chfr and RNF8 synergistically regulate ATM activation. Nat Struct Mol Biol. 2011;18:761-8 pubmed publisher
    ..Collectively, our findings demonstrate that two chromatin-remodeling factors, RNF8 and Chfr, function together to activate ATM and maintain genomic stability in vivo. ..
  6. Mural R, Liu Y, Rosebrock T, Brady J, Hamera S, Connor R, et al. The tomato Fni3 lysine-63-specific ubiquitin-conjugating enzyme and suv ubiquitin E2 variant positively regulate plant immunity. Plant Cell. 2013;25:3615-31 pubmed publisher
    ..These results suggest that Fni3/Sl-Ubc13-2 and Suv regulate the immune response mediated by Fen and other R proteins through Lys-63-linked ubiquitination. ..
  7. Franko J, Ashley C, Xiao W. Molecular cloning and functional characterization of two murine cDNAs which encode Ubc variants involved in DNA repair and mutagenesis. Biochim Biophys Acta. 2001;1519:70-7 pubmed
    ..Ironically, one of two known Mms2 homologs, CROC1, has been linked to cell immortalization and tumorigenesis...
  8. Ashley C, Pastushok L, McKenna S, Ellison M, Xiao W. Roles of mouse UBC13 in DNA postreplication repair and Lys63-linked ubiquitination. Gene. 2002;285:183-91 pubmed
    ..These results suggest that the roles of UBC13 are conserved throughout eukaryotes and that the mouse is an appropriate model for the study of Ubc13-mediated Lys63-linked ubiquitin signaling pathways in humans. ..
  9. Zhao T, Tang X, Umeshappa C, Ma H, Gao H, Deng Y, et al. Simulated Microgravity Promotes Cell Apoptosis Through Suppressing Uev1A/TICAM/TRAF/NF-κB-Regulated Anti-Apoptosis and p53/PCNA- and ATM/ATR-Chk1/2-Controlled DNA-Damage Response Pathways. J Cell Biochem. 2016;117:2138-48 pubmed publisher
    ..J. Cell. Biochem. 117: 2138-2148, 2016. © 2016 Wiley Periodicals, Inc. ..