Trim46

Summary

Gene Symbol: Trim46
Description: tripartite motif-containing 46
Alias: TRIFIC, tripartite motif-containing protein 46, geneY, tripartite, fibronectin type III and C-terminal SPRY motif-containing
Species: mouse
Products:     Trim46

Top Publications

  1. Short K, Cox T. Subclassification of the RBCC/TRIM superfamily reveals a novel motif necessary for microtubule binding. J Biol Chem. 2006;281:8970-80 pubmed
    ..that help define a subfamily that shares an identical domain arrangement (MID1, MID2, TRIM9, TNL, TRIM36, and TRIFIC)...
  2. Vos H, Mockensturm Wilson M, Rood P, Maas A, Duhig T, Gendler S, et al. A tightly organized, conserved gene cluster on mouse chromosome 3 (E3-F1). Mamm Genome. 1995;6:820-2 pubmed
  3. van Beuningen S, Will L, Harterink M, Chazeau A, van Battum E, Frias C, et al. TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays. Neuron. 2015;88:1208-1226 pubmed publisher
    ..Here, we show that the tripartite motif containing (TRIM) protein TRIM46 plays an instructive role in the initial polarization of neuronal cells...
  4. Gumy L, Katrukha E, Grigoriev I, Jaarsma D, Kapitein L, Akhmanova A, et al. MAP2 Defines a Pre-axonal Filtering Zone to Regulate KIF1- versus KIF5-Dependent Cargo Transport in Sensory Neurons. Neuron. 2017;94:347-362.e7 pubmed publisher
    ..We propose that selective axonal cargo trafficking requires the MAP2-defined pre-axonal filtering zone and the ability of cargos to switch between distinct kinesin motor activities. ..