Trappc3

Summary

Gene Symbol: Trappc3
Description: trafficking protein particle complex 3
Alias: 1110058K12Rik, AI835942, AU019197, Bet3, trafficking protein particle complex subunit 3, Bet3 homolog
Species: mouse
Products:     Trappc3

Top Publications

  1. Kim Y, Sohn E, Seo J, Lee K, Lee H, Hwang I, et al. Crystal structure of bet3 reveals a novel mechanism for Golgi localization of tethering factor TRAPP. Nat Struct Mol Biol. 2005;12:38-45 pubmed
    ..Here, the crystal structure of mouse Bet3p (bet3), a conserved TRAPP component, reveals a dimeric structure with hydrophobic channels...
  2. Loh E, Peter F, Subramaniam V, Hong W. Mammalian Bet3 functions as a cytosolic factor participating in transport from the ER to the Golgi apparatus. J Cell Sci. 2005;118:1209-22 pubmed
    ..We describe our biochemical and functional analysis of mammalian Bet3, the most conserved component of the TRAPP complex. Bet3 mRNA is ubiquitously expressed in all tissues...
  3. Menon S, Cai H, Lu H, Dong G, Cai Y, Reinisch K, et al. mBET3 is required for the organization of the TRAPP complexes. Biochem Biophys Res Commun. 2006;350:669-77 pubmed
    ..One subcomplex contains mammalian BET3 (mBET3), mTRS31 and mTRS20, while mBET5 and mTRS23 form a second subcomplex...
  4. Kim Y, Raunser S, Munger C, Wagner J, Song Y, Cygler M, et al. The architecture of the multisubunit TRAPP I complex suggests a model for vesicle tethering. Cell. 2006;127:817-30 pubmed
    ..This study provides the most comprehensive view of a multisubunit vesicle tethering complex to date, based on which a model for the function of this complex, involving Rab1-GTP and long, coiled-coil tethers, is presented. ..