Timm10

Summary

Gene Symbol: Timm10
Description: translocase of inner mitochondrial membrane 10
Alias: Tim13, Timm13a, mitochondrial import inner membrane translocase subunit Tim10, translocase of inner mitochondrial membrane 10 homolog, translocase of inner mitochondrial membrane 13 homolog a
Species: mouse
Products:     Timm10

Top Publications

  1. Bauer M, Rothbauer U, M├╝hlenbein N, Smith R, Gerbitz K, Neupert W, et al. The mitochondrial TIM22 preprotein translocase is highly conserved throughout the eukaryotic kingdom. FEBS Lett. 1999;464:41-7 pubmed
    ..We report the identification, chromosomal localization and expressional analysis of six human family members which represent further candidate genes for neurodegenerative diseases. ..
  2. Ahting U, Floss T, Uez N, Schneider Lohmar I, Becker L, Kling E, et al. Neurological phenotype and reduced lifespan in heterozygous Tim23 knockout mice, the first mouse model of defective mitochondrial import. Biochim Biophys Acta. 2009;1787:371-6 pubmed publisher
    ..It locates to the inner mitochondrial membrane and its own import is dependent on the DDP1/TIM13 complex...
  3. Jin H, Kendall E, Freeman T, Roberts R, Vetrie D. The human family of Deafness/Dystonia peptide (DDP) related mitochondrial import proteins. Genomics. 1999;61:259-67 pubmed
    ..We also describe the expression patterns and chromosomal locations of their genes, which are candidate loci for autosomal recessive neurodegenerative disorders. ..
  4. M├╝hlenbein N, Hofmann S, Rothbauer U, Bauer M. Organization and function of the small Tim complexes acting along the import pathway of metabolite carriers into mammalian mitochondria. J Biol Chem. 2004;279:13540-6 pubmed
    ..We conclude that different mechanisms and specific requirements for import and insertion of mammalian carrier preproteins have evolved in higher eukaryotes. ..