thiolase B


Gene Symbol: thiolase B
Description: acetyl-Coenzyme A acyltransferase 1B
Alias: 3-ketoacyl-CoA thiolase B, peroxisomal, acetyl-CoA acyltransferase B, beta-ketothiolase B, peroxisomal 3-oxoacyl-CoA thiolase B, thiolase B
Species: mouse
Products:     thiolase B

Top Publications

  1. Fidaleo M, Arnauld S, Clémencet M, Chevillard G, Royer M, De Bruycker M, et al. A role for the peroxisomal 3-ketoacyl-CoA thiolase B enzyme in the control of PPAR?-mediated upregulation of SREBP-2 target genes in the liver. Biochimie. 2011;93:876-91 pubmed publisher
    Peroxisomal 3-ketoacyl-CoA thiolase B (Thb) catalyzes the final step in the peroxisomal ?-oxidation of straight-chain acyl-CoAs and is under the transcription control of the nuclear hormone receptor PPAR?...
  2. Chevillard G, Clémencet M, Etienne P, Martin P, Pineau T, Latruffe N, et al. Molecular cloning, gene structure and expression profile of two mouse peroxisomal 3-ketoacyl-CoA thiolase genes. BMC Biochem. 2004;5:3 pubmed
    ..Thiolase A mRNA was mainly expressed in liver and intestine, while thiolase B mRNA essentially exhibited hepatic expression and weaker levels in kidney, intestine and white adipose tissue...
  3. Chevillard G, Clémencet M, Latruffe N, Nicolas Francès V. Targeted disruption of the peroxisomal thiolase B gene in mouse: a new model to study disorders related to peroxisomal lipid metabolism. Biochimie. 2004;86:849-56 pubmed
    ..e. thiolase A, thiolase B and SCP2/thiolase) catalyse the thiolase activity...