Genomes and Genes
Gene Symbol: Tagap
Description: T cell activation Rho GTPase activating protein
Alias: 2610315E15Rik, TRD, Tcd-1, Tcd1, Tcd1a, tcs-1, tcs1, T-cell activation Rho GTPase-activating protein, T-cell activation GTPase-activating protein 1, t-complex distorter 1A
- Himmelbauer H, Artzt K, Barlow D, Fischer Lindahl K, Lyon M, Klein J, et al. Encyclopedia of the mouse genome III. October 1993. Mouse chromosome 17. Mamm Genome. 1993;4 Spec No:S230-52 pubmed
- Schimenti J. Segregation distortion of mouse t haplotypes the molecular basis emerges. Trends Genet. 2000;16:240-3 pubmed..contain mutations that affect embryonic development, male fertility and male transmission ratio distortion (TRD)...
- Liao J, Jijon H, Kim I, Goel G, Doan A, Sokol H, et al. An image-based genetic assay identifies genes in T1D susceptibility loci controlling cellular antiviral immunity in mouse. PLoS ONE. 2014;9:e108777 pubmed publisher..14 candidates identified with high confidence, two candidates were selected for further investigation, Il27 and Tagap. Administration of recombinant IL-27 during viral infection was found to act synergistically with interferon gamma ..