Gene Symbol: Taf10
Description: TATA-box binding protein associated factor 10
Alias: 30kDa, AU041226, TAFII30, Taf2h, transcription initiation factor TFIID subunit 10, TAF(II)30, TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30 kDa, TAFII-30, TATA box binding protein (TBP)-associated factor, RNA polymerase II, H, 30 kDa, mTAFII30, transcription initiation factor TFIID 30 kDa subunit
Indra A, Mohan W, Frontini M, Scheer E, Messaddeq N, Metzger D, et al
. TAF10 is required for the establishment of skin barrier function in foetal, but not in adult mouse epidermis. Dev Biol. 2005;285:28-37 pubmed
..b>TAF10 (formerly TAF(II)30) is shared between TFIID and other transcription regulatory complexes (i.e...
Le Douarin B, Zechel C, Garnier J, Lutz Y, Tora L, Pierrat P, et al
. The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18. EMBO J. 1995;14:2020-33 pubmed
..Interestingly, the TIF1 N-terminal moiety is fused to B-raf in the mouse oncoprotein T18. ..
Gangloff Y, Pointud J, Thuault S, Carre L, Romier C, Muratoglu S, et al
. The TFIID components human TAF(II)140 and Drosophila BIP2 (TAF(II)155) are novel metazoan homologues of yeast TAF(II)47 containing a histone fold and a PHD finger. Mol Cell Biol. 2001;21:5109-21 pubmed
..These conserved domains are critical for yTAF(II)65 function in vivo. Our results therefore identify metazoan homologues of yTAF(II)47 and yTAF(II)65. ..
Kamileri I, Karakasilioti I, Sideri A, Kosteas T, Tatarakis A, Talianidis I, et al
. Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria. Proc Natl Acad Sci U S A. 2012;109:2995-3000 pubmed publisher
..We find that Ercc1(-/-) mice demonstrate striking physiological, metabolic and gene expression parallels with Taf10(-/-) animals carrying a liver-specific transcription factor II D (TFIID) defect in transcription initiation...
Papadopoulos P, GutiÃ©rrez L, Demmers J, Scheer E, Pourfarzad F, Papageorgiou D, et al
. TAF10 Interacts with the GATA1 Transcription Factor and Controls Mouse Erythropoiesis. Mol Cell Biol. 2015;35:2103-18 pubmed publisher
..The contribution of the two TAF10-containing complexes (TFIID, SAGA) to erythropoiesis remains elusive...
Pointud J, Mengus G, Brancorsini S, Monaco L, Parvinen M, Sassone Corsi P, et al
. The intracellular localisation of TAF7L, a paralogue of transcription factor TFIID subunit TAF7, is developmentally regulated during male germ-cell differentiation. J Cell Sci. 2003;116:1847-58 pubmed
..We further show that TAF3, TAF4 and TAF10 are all strongly expressed in early spermatocytes, but that in contrast to TBP and TAF7L, they are downregulated ..
Mohan W, Scheer E, Wendling O, Metzger D, Tora L. TAF10 (TAF(II)30) is necessary for TFIID stability and early embryogenesis in mice. Mol Cell Biol. 2003;23:4307-18 pubmed
b>TAF10 (formerly TAF(II)30), is a component of TFIID and the TATA box-binding protein (TBP)-free TAF-containing complexes (TFTC/PCAF/STAGA)...
Metzger D, Scheer E, Soldatov A, Tora L. Mammalian TAF(II)30 is required for cell cycle progression and specific cellular differentiation programmes. EMBO J. 1999;18:4823-34 pubmed
..Thus, TAF(II)30 is not indispensable for class II gene transcription in general, but seems to be required for the expression of a subset of genes. ..
Lange A, Wickström S, Jakobson M, Zent R, Sainio K, Fassler R. Integrin-linked kinase is an adaptor with essential functions during mouse development. Nature. 2009;461:1002-6 pubmed publisher
..Thus, we provide genetic evidence that the kinase activity of Ilk is dispensable for mammalian development; however, an interaction between Ilk and alpha-parvin is critical for kidney development. ..