Gene Symbol: Srm
Description: spermidine synthase
Alias: AA407669, SpdST, SpdSy, spermidine synthase, putrescine aminopropyltransferase
Species: mouse
Products:     Srm

Top Publications

  1. Kauppinen L, Myöhänen S, Halmekyto M, Alhonen L, Janne J. Transgenic mice over-expressing the human spermidine synthase gene. Biochem J. 1993;293 ( Pt 2):513-6 pubmed
    We have generated a transgenic mouse line harbouring the functional (chromosome-1-derived) human spermidine synthase (EC gene in their genome...
  2. Shi C, Welsh P, Sass Kuhn S, Wang X, McCloskey D, Pegg A, et al. Characterization of transgenic mice with overexpression of spermidine synthase. Amino Acids. 2012;42:495-505 pubmed publisher
    ..enhancer/chicken ?-actin promoter (CAG) was utilized to generate transgenic mice that overexpress human spermidine synthase (SpdS) to determine the impact of elevated spermidine synthase activity on murine development and ..
  3. Lopez Garcia C, Lopez Contreras A, Cremades A, Castells M, Penafiel R. Transcriptomic analysis of polyamine-related genes and polyamine levels in placenta, yolk sac and fetus during the second half of mouse pregnancy. Placenta. 2009;30:241-9 pubmed publisher
    ..Our results suggest that the elevated polyamine biosynthetic activity of mouse placenta is required to satisfy the high demand of polyamines required by the growing fetus, during the later period of pregnancy. ..
  4. Wada M, Amano D, Hosoda H, Shirahata A, Samejima K, Pegg A. Primary structure of rat spermidine synthase: an example of refining the cDNA-derived amino acid sequence. Biol Pharm Bull. 1999;22:889-95 pubmed
    The primary structure of rat spermidine synthase having the N-terminal acetylated methionine and 98.7% homology with that of the mouse enzyme is presented using a limited amount of the homogeneous enzyme...
  5. Myöhänen S, Wahlfors J, Alhonen L, Janne J. Nucleotide sequence of mouse spermidine synthase cDNA. DNA Seq. 1994;4:343-6 pubmed
    The nucleotide sequence of mouse cDNA for spermidine synthase appeared to contain 75 nucleotides of 5' untranslated region, an open reading frame of 909 nucleotides and 297 nucleotides of 3' untranslated region...