Gene Symbol: SRCL
Description: collectin sub-family member 12
Alias: CL-P1, SRCL, Scara4, collectin-12, collectin placenta protein 1, scavenger receptor with C-type lectin
Nakamura K, Funakoshi H, Tokunaga F, Nakamura T. Molecular cloning of a mouse scavenger receptor with C-type lectin (SRCL)(1), a novel member of the scavenger receptor family. Biochim Biophys Acta. 2001;1522:53-8 pubmed
The cDNA clone encoding a mouse scavenger receptor with C-type lectin (SRCL), a novel member of the scavenger receptor family, has been isolated from a mouse embryonic cDNA library...
Feinberg H, Taylor M, Weis W. Scavenger receptor C-type lectin binds to the leukocyte cell surface glycan Lewis(x) by a novel mechanism. J Biol Chem. 2007;282:17250-8 pubmed
The scavenger receptor C-type lectin (SRCL) is unique in the family of class A scavenger receptors, because in addition to binding sites for oxidized lipoproteins it also contains a C-type carbohydrate-recognition domain (CRD) that ..
Jang S, Ohtani K, Fukuoh A, Yoshizaki T, Fukuda M, Motomura W, et al
. Scavenger receptor collectin placenta 1 (CL-P1) predominantly mediates zymosan phagocytosis by human vascular endothelial cells. J Biol Chem. 2009;284:3956-65 pubmed publisher
..Furthermore, we confirmed that CL-P1 is expressed in human and murine vascular endothelial layers. Our results demonstrated that CL-P1 predominantly mediated phagocytosis for fungi in vascular endothelia. ..
Prabhudas M, Bowdish D, Drickamer K, Febbraio M, Herz J, Kobzik L, et al
. Standardizing scavenger receptor nomenclature. J Immunol. 2014;192:1997-2006 pubmed publisher
..The purpose of this article is to describe the proposed mammalian nomenclature and classification developed at the workshop and to solicit additional feedback from the broader research community. ..
Ohtani K, Suzuki Y, Eda S, Kawai T, Kase T, Keshi H, et al
. The membrane-type collectin CL-P1 is a scavenger receptor on vascular endothelial cells. J Biol Chem. 2001;276:44222-8 pubmed
..These results indicate that CL-P1 might play important roles in host defenses that are different from those of soluble collectins in innate immunity. ..