S3 12

Summary

Gene Symbol: S3 12
Description: perilipin 4
Alias: S3-12, mKIAA1881, adipocyte protein S3-12, perilipin-4, plasma membrane associated protein, S3-12
Species: mouse

Top Publications

  1. ncbi Adipocyte protein S3-12 coats nascent lipid droplets
    Nathan E Wolins
    Department of Medicine, Division of Endocrinology, Metabolism, and Lipid Research, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Biol Chem 278:37713-21. 2003
  2. pmc The expression and function of fatty acid transport protein-2 and -4 in the murine placenta
    Takuya Mishima
    Department of Obstetrics, Gynecology and Reproductive Sciences, Magee Womens Research Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
    PLoS ONE 6:e25865. 2011
  3. pmc Inactivation of Plin4 downregulates Plin5 and reduces cardiac lipid accumulation in mice
    Weiqin Chen
    Diabetes and Endocrinology Research Center, Section of Diabetes and Endocrinology, Departments of Medicine, Molecular and Cellular Biology and Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Am J Physiol Endocrinol Metab 304:E770-9. 2013
  4. ncbi Cloning of cell-specific secreted and surface proteins by subtractive antibody screening
    P E Scherer
    Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA
    Nat Biotechnol 16:581-6. 1998
  5. ncbi Adipose tissue expression of the lipid droplet-associating proteins S3-12 and perilipin is controlled by peroxisome proliferator-activated receptor-gamma
    Knut Tomas Dalen
    Institute for Nutrition Research, University of Oslo, Blindern, N 0316 Oslo, Norway
    Diabetes 53:1243-52. 2004
  6. ncbi S3-12, Adipophilin, and TIP47 package lipid in adipocytes
    Nathan E Wolins
    Department of Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Biol Chem 280:19146-55. 2005
  7. ncbi Ligand-activated peroxisome proliferator activated receptor gamma alters placental morphology and placental fatty acid uptake in mice
    W Timothy Schaiff
    Washington University School of Medicine, Department of Obstetrics and Gynecology, Campus Box 8064, 4566 Scott Avenue, St Louis, Missouri 63110, USA
    Endocrinology 148:3625-34. 2007
  8. pmc Consequences of lipid droplet coat protein downregulation in liver cells: abnormal lipid droplet metabolism and induction of insulin resistance
    Ming Bell
    Geriatric Research, Education and Clinical Center, Baltimore Veterans Affairs Health Care Center, Division of Gerontology, Department of Medicine, School of Medicine, University of Maryland, Baltimore, Maryland, USA
    Diabetes 57:2037-45. 2008

Detail Information

Publications8

  1. ncbi Adipocyte protein S3-12 coats nascent lipid droplets
    Nathan E Wolins
    Department of Medicine, Division of Endocrinology, Metabolism, and Lipid Research, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Biol Chem 278:37713-21. 2003
    ..This study reports for the first time the early morphological events in the genesis and maturation of adipocyte lipid droplets...
  2. pmc The expression and function of fatty acid transport protein-2 and -4 in the murine placenta
    Takuya Mishima
    Department of Obstetrics, Gynecology and Reproductive Sciences, Magee Womens Research Institute, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
    PLoS ONE 6:e25865. 2011
    ..We surmised that placental FATPs are germane for fetal growth, and are regulated during hypoxic stress, which is associated with reduced fat supply to the fetus...
  3. pmc Inactivation of Plin4 downregulates Plin5 and reduces cardiac lipid accumulation in mice
    Weiqin Chen
    Diabetes and Endocrinology Research Center, Section of Diabetes and Endocrinology, Departments of Medicine, Molecular and Cellular Biology and Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA
    Am J Physiol Endocrinol Metab 304:E770-9. 2013
    ..In conclusion, inactivation of Plin4 downregulates Plin5 and reduces cardiac lipid accumulation in mice...
  4. ncbi Cloning of cell-specific secreted and surface proteins by subtractive antibody screening
    P E Scherer
    Whitehead Institute for Biomedical Research, Cambridge, MA 02142, USA
    Nat Biotechnol 16:581-6. 1998
    ..We describe several of these, including a novel plasma membrane-associated protein, S3-12...
  5. ncbi Adipose tissue expression of the lipid droplet-associating proteins S3-12 and perilipin is controlled by peroxisome proliferator-activated receptor-gamma
    Knut Tomas Dalen
    Institute for Nutrition Research, University of Oslo, Blindern, N 0316 Oslo, Norway
    Diabetes 53:1243-52. 2004
    ....
  6. ncbi S3-12, Adipophilin, and TIP47 package lipid in adipocytes
    Nathan E Wolins
    Department of Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Biol Chem 280:19146-55. 2005
    ....
  7. ncbi Ligand-activated peroxisome proliferator activated receptor gamma alters placental morphology and placental fatty acid uptake in mice
    W Timothy Schaiff
    Washington University School of Medicine, Department of Obstetrics and Gynecology, Campus Box 8064, 4566 Scott Avenue, St Louis, Missouri 63110, USA
    Endocrinology 148:3625-34. 2007
    ..These results demonstrate that in vivo activation of PPARgamma modulates placental morphology and fatty acid accumulation...
  8. pmc Consequences of lipid droplet coat protein downregulation in liver cells: abnormal lipid droplet metabolism and induction of insulin resistance
    Ming Bell
    Geriatric Research, Education and Clinical Center, Baltimore Veterans Affairs Health Care Center, Division of Gerontology, Department of Medicine, School of Medicine, University of Maryland, Baltimore, Maryland, USA
    Diabetes 57:2037-45. 2008
    ..Our hypothesis is that PAT proteins modulate LD metabolism and therefore insulin resistance...