Gene Symbol: Rpl19
Description: ribosomal protein L19
Alias: 60S ribosomal protein L19
Species: mouse
Products:     Rpl19

Top Publications

  1. Meyuhas O, Perry R. Construction and identification of cDNA clones for mouse ribosomal proteins: application for the study of r-protein gene expression. Gene. 1980;10:113-29 pubmed
  2. Hou Q, Gorski J. Estrogen receptor and progesterone receptor genes are expressed differentially in mouse embryos during preimplantation development. Proc Natl Acad Sci U S A. 1993;90:9460-4 pubmed
    ..These results provide a basis for determining the direct role of estrogen and progesterone in preimplantation embryos. ..
  3. Hiroi H, Momoeda M, Inoue S, Tsuchiya F, Matsumi H, Tsutsumi O, et al. Stage-specific expression of estrogen receptor subtypes and estrogen responsive finger protein in preimplantational mouse embryos. Endocr J. 1999;46:153-8 pubmed
    ..The stage specific expression of ER alpha and ER beta along with detection of the product of the estrogen responsive gene in early preimplantation embryos may indicate the possible physiological roles of estrogen in early embryogenesis. ..
  4. Kushnir M, Dresner E, Mandel S, Gozes I. Silencing of the ADNP-family member, ADNP2, results in changes in cellular viability under oxidative stress. J Neurochem. 2008;105:537-45 pubmed publisher
    ..These findings represent an initial characterization of ADNP2 and suggest that this gene product may have an important function in brain by playing a role in cellular survival pathways. ..
  5. Andriopoulos B, Corradini E, Xia Y, Faasse S, Chen S, Grgurevic L, et al. BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism. Nat Genet. 2009;41:482-7 pubmed publisher
    ..These data support a key role for BMP6 as a ligand for hemojuvelin and an endogenous regulator of hepcidin expression and iron metabolism in vivo. ..
  6. Dong Y, Sui L, Yamaguchi F, Kamitori K, Hirata Y, Hossain M, et al. Phosphatase and tensin homolog deleted on chromosome 10 regulates sensory cell proliferation and differentiation of hair bundles in the mammalian cochlea. Neuroscience. 2010;170:1304-13 pubmed publisher
  7. Nakamura T, Onno M, Mariage Samson R, Hillova J, Hill M. Nucleotide sequence of mouse L19 ribosomal protein cDNA isolated in screening with tre oncogene probes. DNA Cell Biol. 1990;9:697-703 pubmed
    ..Comparison with the weakly hybridizing tre gene probe showed stretches of homology that were, however, too short to be taken into consideration. We conclude that the 11-5 sequence encodes the mouse L19 ribosomal protein. ..
  8. D EUSTACHIO P, Meyuhas O, Ruddle F, Perry R. Chromosomal distribution of ribosomal protein genes in the mouse. Cell. 1981;24:307-12 pubmed
  9. Smith S, French M, Julian J, Paria B, Dey S, Carson D. Expression of heparan sulfate proteoglycan (perlecan) in the mouse blastocyst is regulated during normal and delayed implantation. Dev Biol. 1997;184:38-47 pubmed
    ..Moreover, perlecan protein expression also is attenuated during delayed implantation and appears to increase in response to nidatory estrogen, perhaps via the increased translation of preexisting perlecan mRNA. ..

More Information


  1. Chen P, Zindy F, Abdala C, Liu F, Li X, Roussel M, et al. Progressive hearing loss in mice lacking the cyclin-dependent kinase inhibitor Ink4d. Nat Cell Biol. 2003;5:422-6 pubmed
    ..Our results identify a novel mechanism underlying a non-syndromic form of progressive hearing loss in mice. ..
  2. Wagner K, Schulz P, Scholz A, Wiedenmann B, Menrad A. The targeted immunocytokine L19-IL2 efficiently inhibits the growth of orthotopic pancreatic cancer. Clin Cancer Res. 2008;14:4951-60 pubmed publisher
    ..These preclinical results strongly encourage the initiation of clinical studies using L19-IL-2 in pancreatic cancer. ..
  3. Czabanka M, Parmaksiz G, Bayerl S, Nieminen M, Trachsel E, Menssen H, et al. Microvascular biodistribution of L19-SIP in angiogenesis targeting strategies. Eur J Cancer. 2011;47:1276-84 pubmed publisher
    ..Microvascular biodistribution is enhanced in anti-angiogenic-therapy resistant tumour vessels. ..
  4. Su Y, Sugiura K, Sun F, Pendola J, Cox G, Handel M, et al. MARF1 regulates essential oogenic processes in mice. Science. 2012;335:1496-9 pubmed publisher
    ..Therefore MARF1, by suppressing levels of specific transcripts, is an essential regulator of important oogenic processes leading to female fertility and the development of healthy offspring. ..
  5. Sugihara Y, Sadohara E, Yonezawa K, Kugo M, Oshima K, Matsuda T, et al. Identification and expression of an autosomal paralogue of ribosomal protein S4, X-linked, in mice: potential involvement of testis-specific ribosomal proteins in translation and spermatogenesis. Gene. 2013;521:91-9 pubmed publisher