Gene Symbol: Rab32
Description: RAB32, member RAS oncogene family
Alias: 2810011A17Rik, AU022057, ras-related protein Rab-32
Bui M, Gilady S, Fitzsimmons R, Benson M, Lynes E, Gesson K, et al
. Rab32 modulates apoptosis onset and mitochondria-associated membrane (MAM) properties. J Biol Chem. 2010;285:31590-602 pubmed publisher
..Our results now show that the GTPase Rab32 localizes to the ER and mitochondria, and we identify this protein as a regulator of MAM properties...
Kirov J, Adkisson M, Nava A, Cipollone A, Willis B, Engelhard E, et al
. Reporter Gene Silencing in Targeted Mouse Mutants Is Associated with Promoter CpG Island Methylation. PLoS ONE. 2015;10:e0134155 pubmed publisher
..The results support the conclusion that there is promoter silencing in a subset of mutants carrying the tm1a allele. The features of targeted genes which promote local silencing when targeted remain unknown. ..
Pei Y, Yue L, Zhang W, Wang Y, Wen B, Zhong L, et al
. Improvement in Mouse iPSC Induction by Rab32 Reveals the Importance of Lipid Metabolism during Reprogramming. Sci Rep. 2015;5:16539 pubmed publisher
..the efficiency of iPSC generation using Oct4, Sox2, Klf4 (termed OSK) plus one additional gene, we found that Rab32 improved reprogramming efficiency...
SpanÃ² S, Gao X, Hannemann S, Lara Tejero M, GalÃ¡n J. A Bacterial Pathogen Targets a Host Rab-Family GTPase Defense Pathway with a GAP. Cell Host Microbe. 2016;19:216-26 pubmed publisher
..The Rab-family GTPase Rab32 was previously shown to restrict the intracellular human pathogen Salmonella Typhi, but its potential broader role ..
Li Y, Wang Y, Zou L, Tang X, Yang Y, Ma L, et al
. Analysis of the Rab GTPase Interactome in Dendritic Cells Reveals Anti-microbial Functions of the Rab32 Complex in Bacterial Containment. Immunity. 2016;44:422-37 pubmed publisher
..Driven by this analysis, we investigated dynamic changes to the Rab32 subnetwork in DCs induced by L...
Cohen Solal K, Sood R, Marin Y, Crespo Carbone S, Sinsimer D, Martino J, et al
. Identification and characterization of mouse Rab32 by mRNA and protein expression analysis. Biochim Biophys Acta. 2003;1651:68-75 pubmed
..Cloning of human RAB32 was recently described. Presently, we report the cloning and characterization of the mouse homologue of Rab32...
Tamura K, Ohbayashi N, Maruta Y, Kanno E, Itoh T, Fukuda M. Varp is a novel Rab32/38-binding protein that regulates Tyrp1 trafficking in melanocytes. Mol Biol Cell. 2009;20:2900-8 pubmed publisher
Two small GTPase Rabs, Rab32 and Rab38, have recently been proposed to regulate trafficking of melanogenic enzymes to melanosomes in mammalian epidermal melanocytes; however, the exact molecular mechanism of Rab32/38-mediated transport ..
Spanò S, Galan J. A Rab32-dependent pathway contributes to Salmonella typhi host restriction. Science. 2012;338:960-3 pubmed publisher
..This effector proteolytically targeted Rab32, which controls traffic to lysosome-related organelles in conjunction with components of the biogenesis of ..
Marubashi S, Shimada H, Fukuda M, Ohbayashi N. RUTBC1 Functions as a GTPase-activating Protein for Rab32/38 and Regulates Melanogenic Enzyme Trafficking in Melanocytes. J Biol Chem. 2016;291:1427-40 pubmed publisher
Two cell type-specific Rab proteins, Rab32 and Rab38 (Rab32/38), have been proposed as regulating the trafficking of melanogenic enzymes, including tyrosinase and tyrosinase-related protein 1 (Tyrp1), to melanosomes in melanocytes...