Gene Symbol: Ptpn7
Description: protein tyrosine phosphatase, non-receptor type 7
Alias: BPTP-4, C920001D21Rik, HEPTP, LC-PTP, LPTP, tyrosine-protein phosphatase non-receptor type 7, hematopoietic protein-tyrosine phosphatase
Species: mouse
Products:     Ptpn7

Top Publications

  1. Gronda M, Arab S, Iafrate B, Suzuki H, Zanke B. Hematopoietic protein tyrosine phosphatase suppresses extracellular stimulus-regulated kinase activation. Mol Cell Biol. 2001;21:6851-8 pubmed
    ..b>Hematopoietic protein tyrosine phosphatase (HePTP) is a hematopoiesis-specific cytoplasmic protein tyrosine phosphatase whose expression is ..
  2. Magilavy D, Foys K, Gajewski T. Liver of MRL/lpr mice contain interleukin-4-producing lymphocytes and accessory cells that support the proliferation of Th2 helper T lymphocyte clones. Eur J Immunol. 1992;22:2359-65 pubmed
    ..These results suggest that the activation of Th2 cells by hepatic NPC and production of IL-4 by HL may contribute to the immunologic aberrations in the MRL/lpr mouse strain. ..
  3. McAlees J, Sanders V. Hematopoietic protein tyrosine phosphatase mediates beta2-adrenergic receptor-induced regulation of p38 mitogen-activated protein kinase in B lymphocytes. Mol Cell Biol. 2009;29:675-86 pubmed publisher
    ..Here we show that the beta(2)AR-induced increase in p38 MAPK activation occurred via a hematopoietic protein tyrosine phosphatase (HePTP)-mediated cross talk between PKA and p38 MAPK...
  4. Seo H, Lee I, Park J, Park S, Lee D, Park B, et al. Role of protein tyrosine phosphatase non-receptor type 7 in the regulation of TNF-? production in RAW 264.7 macrophages. PLoS ONE. 2013;8:e78776 pubmed publisher
    ..Protein tyrosine phosphatase non-receptor type 7 (PTPN7), a member of the phosphatase family, specifically inactivates mitogen-activated protein kinases (MAPKs)...