Gene Symbol: Pmscl1
Description: exosome component 9
Alias: PM/Scl-75, Pmscl1, RRP45, exosome complex component RRP45, P75 polymyositis-scleroderma overlap syndrome-associated autoantigen, autoantigen PM/Scl 1, exosome complex exonuclease RRP45, polymyositis/scleroderma autoantigen 1, polymyositis/scleroderma autoantigen 75 kDa
Species: mouse
Products:     Pmscl1

Top Publications

  1. Bliskovski V, Liddell R, Ramsay E, Miller M, Mock B. Structure and localization of mouse Pmscl1 and Pmscl2 genes. Genomics. 2000;64:106-10 pubmed
    ..patients with polymyositis-scleoderma overlap syndrome (PM-SCL) recognize two antigenically unrelated proteins, PMSCL1 and PMSCL2...
  2. Bliskovsky V, Ramsay E, Scott J, DuBois W, Shi W, Zhang S, et al. Frap, FKBP12 rapamycin-associated protein, is a candidate gene for the plasmacytoma resistance locus Pctr2 and can act as a tumor suppressor gene. Proc Natl Acad Sci U S A. 2003;100:14982-7 pubmed
    ..By analogy, human cancer may also result from the combined effects of several inefficient alleles. ..
  3. Hao L, Vassena R, Wu G, Han Z, Cheng Y, Latham K, et al. The unfolded protein response contributes to preimplantation mouse embryo death in the DDK syndrome. Biol Reprod. 2009;80:944-53 pubmed publisher
    ..Our results indicate that the unfolded protein response is induced in embryos destined to die of DDK syndrome and that the embryonic death observed is associated with inability to resolve the associated ER stress. ..