Pcbp3

Summary

Gene Symbol: Pcbp3
Description: poly(rC) binding protein 3
Alias: AlphaCP-3, poly(rC)-binding protein 3, alpha-CP3
Species: mouse
Products:     Pcbp3

Top Publications

  1. Kang D, Song K, Choi H, Law P, Wei L, Loh H. Novel dual-binding function of a poly (C)-binding protein 3, transcriptional factor which binds the double-strand and single-stranded DNA sequence. Gene. 2012;501:33-8 pubmed publisher
    ..mRNA stabilization or translational activation/silencing). This study reports a novel dual-binding function for PCBP3, a member of the PCBP family...
  2. Makeyev A, Liebhaber S. Identification of two novel mammalian genes establishes a subfamily of KH-domain RNA-binding proteins. Genomics. 2000;67:301-16 pubmed
    ..These data establish a new subfamily of genes predicted to encode closely related KH-containing RNA-binding proteins with potential functions in posttranscriptional controls. ..
  3. Hirano M, Noda T. Genomic organization of the mouse Msh4 gene producing bicistronic, chimeric and antisense mRNA. Gene. 2004;342:165-77 pubmed
    ..exons of delta and the first exon of epsilon are respectively mapped to the Hspa5 locus on chromosome 2 and the Pcbp3 locus on chromosome 10; the remaining exons of both variants are mapped to the Msh4 locus on chromosome 3...
  4. Choi H, Kim C, Hwang C, Song K, Law P, Wei L, et al. Novel function of the poly(C)-binding protein alpha CP3 as a transcriptional repressor of the mu opioid receptor gene. FASEB J. 2007;21:3963-73 pubmed
    ..Our data suggest that alphaCP3 can function as a repressor of MOR transcription dependent on the MOR poly(C) sequence. We demonstrate for the first time a role of alphaCP3 as a transcriptional repressor in MOR gene regulation. ..