Genomes and Genes
Gene Symbol: Nap1
Description: NCK-associated protein 1
Alias: C79304, H19, Hem-2, Hem2, Nap1, mKIAA0587, mh19, p125Nap1, nck-associated protein 1, brain protein H19, membrane-associated protein HEM-2
- Afzal T, Luong L, Chen D, Zhang C, Yang F, Chen Q, et al. NCK Associated Protein 1 Modulated by miRNA-214 Determines Vascular Smooth Muscle Cell Migration, Proliferation, and Neointima Hyperplasia. J Am Heart Assoc. 2016;5: pubmed..Gene and protein biochemical assays, including proteomic analyses, showed that NCK associated protein 1 (NCKAP1)-a major component of the WAVE complex that regulates lamellipodia formation and cell motility-..
- Migeotte I, Omelchenko T, Hall A, Anderson K. Rac1-dependent collective cell migration is required for specification of the anterior-posterior body axis of the mouse. PLoS Biol. 2010;8:e1000442 pubmed publisher..The data show that Rac1-mediated epithelial migration of the AVE is a crucial step in the establishment of the mammalian body plan and suggest that Rac1 is essential for collective migration in mammalian tissues...
- Baumgartner S, Martin D, Chiquet Ehrismann R, Sutton J, Desai A, Huang I, et al. The HEM proteins: a novel family of tissue-specific transmembrane proteins expressed from invertebrates through mammals with an essential function in oogenesis. J Mol Biol. 1995;251:41-9 pubmed..Of the vertebrate HEM family members, the mammalian Hem-1 gene is expressed only in cells of hematopoietic origin, while Hem-2 is preferentially expressed in brain, heart, liver and testis. ..
- Kato K. A Collection of cDNA Clones with Specific Expression Patterns in Mouse Brain. Eur J Neurosci. 1990;2:704-711 pubmed..Among them seven clones were especially abundant in specific nuclei, and three in specific fibre bundles. These clones will be useful in defining new subpopulations of brain cells characterized by different gene expression. ..
- Maddala R, Chauhan B, Walker C, Zheng Y, Robinson M, Lang R, et al. Rac1 GTPase-deficient mouse lens exhibits defects in shape, suture formation, fiber cell migration and survival. Dev Biol. 2011;360:30-43 pubmed publisher..Lens fiber cell N-cadherin/?-catenin/Rap1/Nectin-based cell-cell junction formation and WAVE-2/Abi-2/Nap1-regulated actin polymerization were impaired in the Rac1 deficient mice...