Gene Symbol: Myo1b
Description: myosin IB
Alias: AA406997, MIH-L, MMIa, unconventional myosin-Ib, MMI-alpha, Myosin IA (Myosin I alpha) (MMI-alpha) (MMIa) (MIH-L), molecular motor, myosin I alpha, myosin-Ib
Sherr E, Joyce M, Greene L. Mammalian myosin I alpha, I beta, and I gamma: new widely expressed genes of the myosin I family. J Cell Biol. 1993;120:1405-16 pubmed
..2-kb polymerase chain reaction products that correspond to novel mammalian myosin I genes designated MMI alpha, MMI beta, MMI gamma...
Koslovsky J, Qian C, Jiang X, Mercer J. Molecular cloning of a mouse myosin I expressed in brain. FEBS Lett. 1993;320:121-4 pubmed
..Northern analysis demonstrates that this myosin heavy chain, unlike the brush border myosins, is expressed in many tissues. ..
Kawamoto S, Matsumoto Y, Mizuno K, Okubo K, Matsubara K. Expression profiles of active genes in human and mouse livers. Gene. 1996;174:151-8 pubmed
..This comparative analysis using expression profiling should find a wide application in comparative biology. ..
Dumont R, Zhao Y, Holt J, Bähler M, Gillespie P. Myosin-I isozymes in neonatal rodent auditory and vestibular epithelia. J Assoc Res Otolaryngol. 2002;3:375-89 pubmed
..Using RT-PCR, we found prominent expression of three isozymes, Myo1b (also known as myosin-Ia or myr 1). Myo1c (myosin-Ib or myr 2). and Myo1e (myr 3)...
Bose A, Guilherme A, Robida S, Nicoloro S, Zhou Q, Jiang Z, et al
. Glucose transporter recycling in response to insulin is facilitated by myosin Myo1c. Nature. 2002;420:821-4 pubmed
..Thus, myosin Myo1c functions in a PI(3)K-independent insulin signalling pathway that controls the movement of intracellular GLUT4-containing vesicles to the plasma membrane. ..
Almeida C, Yamada A, Tenza D, Louvard D, Raposo G, Coudrier E. Myosin 1b promotes the formation of post-Golgi carriers by regulating actin assembly and membrane remodelling at the trans-Golgi network. Nat Cell Biol. 2011;13:779-89 pubmed publisher
..Our results provide evidence that actin and myosin 1 regulate organelle shape and uncover an important function for myosin 1b in the initiation of post-Golgi carrier formation by regulating actin assembly and remodelling TGN membranes. ..