Gene Symbol: Mybpc1
Description: myosin binding protein C, slow-type
Alias: 8030451F13Rik, myosin-binding protein C, slow-type, MyBP-C slow, Slow-type C-protein
Species: mouse
Products:     Mybpc1

Top Publications

  1. Schiaffino S, Reggiani C. Molecular diversity of myofibrillar proteins: gene regulation and functional significance. Physiol Rev. 1996;76:371-423 pubmed
    ..Both myosin and troponin isoforms contribute to the differences in the resistance to fatigue of muscle fibers...
  2. Gautel M, F├╝rst D, Cocco A, Schiaffino S. Isoform transitions of the myosin binding protein C family in developing human and mouse muscles: lack of isoform transcomplementation in cardiac muscle. Circ Res. 1998;82:124-9 pubmed
    ..This suggests that transcomplementation of MyBP-C isoforms is possible in skeletal but not cardiac muscle. ..
  3. Kurasawa M, Sato N, Matsuda A, Koshida S, Totsuka T, Obinata T. Differential expression of C-protein isoforms in developing and degenerating mouse striated muscles. Muscle Nerve. 1999;22:196-207 pubmed
    ..We also suggest that the expression of S isoform may be stimulated in degenerating human dystrophic muscles. ..
  4. Cohen S, Brault J, Gygi S, Glass D, Valenzuela D, Gartner C, et al. During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation. J Cell Biol. 2009;185:1083-95 pubmed publisher
    ..Because these proteins stabilize the thick filament, their selective ubiquitylation may facilitate thick filament disassembly. However, the thin filament components decreased by a mechanism not requiring MuRF1...
  5. Jin C, Chen J, Meng Q, Carreira V, Tam N, Geh E, et al. Deciphering gene expression program of MAP3K1 in mouse eyelid morphogenesis. Dev Biol. 2013;374:96-107 pubmed publisher
    ..Using LCM and expression array, our studies have uncovered novel molecular signatures of MAP3K1 in embryonic eyelid closure. ..
  6. Ackermann M, Patel P, Valenti J, Takagi Y, Homsher E, Sellers J, et al. Loss of actomyosin regulation in distal arthrogryposis myopathy due to mutant myosin binding protein-C slow. FASEB J. 2013;27:3217-28 pubmed publisher