Mtmr9

Summary

Gene Symbol: Mtmr9
Description: myotubularin related protein 9
Alias: 9430075G12Rik, AA516943, AF073881, LIP-STYX, MTMR8, mMTMH3, myotubularin-related protein 9
Species: mouse
Products:     Mtmr9

Top Publications

  1. Mochizuki Y, Majerus P. Characterization of myotubularin-related protein 7 and its binding partner, myotubularin-related protein 9. Proc Natl Acad Sci U S A. 2003;100:9768-73 pubmed
    ..protein was found in an anti-MTMR7 immunoprecipitate from N1E-115 cells and identified as MTM-related protein 9 (MTMR9) by tandem mass spectrometry. The coiled-coil domain of MTMR9 was sufficient for binding to MTMR7...
  2. Guo L, Martens C, Bruno D, Porcella S, Yamane H, Caucheteux S, et al. Lipid phosphatases identified by screening a mouse phosphatase shRNA library regulate T-cell differentiation and protein kinase B AKT signaling. Proc Natl Acad Sci U S A. 2013;110:E1849-56 pubmed publisher
    ..We concentrated on two lipid phosphatases, the myotubularin-related protein (MTMR)9 and -7. Silencing MTMR9 by shRNA or siRNA resulted in enhanced T-helper (Th)1 differentiation and increased Th1 protein kinase B (PKB)/AKT ..
  3. Maekawa M, Terasaka S, Mochizuki Y, Kawai K, Ikeda Y, Araki N, et al. Sequential breakdown of 3-phosphorylated phosphoinositides is essential for the completion of macropinocytosis. Proc Natl Acad Sci U S A. 2014;111:E978-87 pubmed publisher
    ..that mammalian phosphoinositide phosphatase MTMR6 that dephosphorylates PI(3)P to PI, and its binding partner MTMR9, are required for macropinocytosis...
  4. Laporte J, Blondeau F, Buj Bello A, Tentler D, Kretz C, Dahl N, et al. Characterization of the myotubularin dual specificity phosphatase gene family from yeast to human. Hum Mol Genet. 1998;7:1703-12 pubmed
    ..Comparison of the various genes allowed construction of a phylogenetic tree and reveals conserved residues which may be essential for function. These genes may be good candidates for other genetic diseases. ..
  5. Claycombe K, Xue B, Mynatt R, Zemel M, Moustaid Moussa N. Regulation of leptin by agouti. Physiol Genomics. 2000;2:101-5 pubmed