Gene Symbol: Mrpl58
Description: mitochondrial ribosomal protein L58
Alias: 1110001A02Rik, 1110002E03Rik, Ict1, MRP-L58, peptidyl-tRNA hydrolase ICT1, mitochondrial, 39S ribosomal protein L58, mitochondrial, immature colon carcinoma transcript 1 protein homolog
Species: mouse
Products:     Mrpl58

Top Publications

  1. Handa Y, Hikawa Y, Tochio N, Kogure H, Inoue M, Koshiba S, et al. Solution structure of the catalytic domain of the mitochondrial protein ICT1 that is essential for cell vitality. J Mol Biol. 2010;404:260-73 pubmed publisher
    The ICT1 protein was recently reported to be a component of the human mitoribosome and to have codon-independent peptidyl-tRNA hydrolysis activity via its conserved GGQ motif, although little is known about the detailed mechanism...
  2. Feaga H, Quickel M, Hankey Giblin P, Keiler K. Human Cells Require Non-stop Ribosome Rescue Activity in Mitochondria. PLoS Genet. 2016;12:e1005964 pubmed publisher
    ..The eukaryotic protein ICT1 (Q14197) is homologous to ArfB...