Gene Symbol: Mpzl2
Description: myelin protein zero-like 2
Alias: Eva, Eva1, myelin protein zero-like protein 2, epithelial V-like antigen 1
DeMonte L, Porcellini S, Tafi E, Sheridan J, Gordon J, Depreter M, et al
. EVA regulates thymic stromal organisation and early thymocyte development. Biochem Biophys Res Commun. 2007;356:334-40 pubmed
Epithelial V-like antigen (EVA) is an immunoglobulin-like adhesion molecule identified in a screen for molecules developmentally regulated at the DN to DP progression in thymocyte development...
Guttinger M, Sutti F, Panigada M, Porcellini S, Merati B, Mariani M, et al
. Epithelial V-like antigen (EVA), a novel member of the immunoglobulin superfamily, expressed in embryonic epithelia with a potential role as homotypic adhesion molecule in thymus histogenesis. J Cell Biol. 1998;141:1061-71 pubmed
..identification of a gene encoding a new member of the immunoglobulin superfamily, named epithelial V-like antigen (EVA), which is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression...
Teesalu T, Grassi F, Guttinger M. Expression pattern of the epithelial v-like antigen (Eva) transcript suggests a possible role in placental morphogenesis. Dev Genet. 1998;23:317-23 pubmed
..Epithelial V-like Antigen (Eva) is a novel homophilic adhesion molecule of the immunoglobulin superfamily, which during mouse embryonic ..
Chatterjee G, Carrithers L, Carrithers M. Epithelial V-like antigen regulates permeability of the blood-CSF barrier. Biochem Biophys Res Commun. 2008;372:412-7 pubmed publisher
Epithelial V-like antigen (EVA), a CD3-binding immunoglobulin-like protein, regulates embryonic thymic development...
Sewell W, Sparrow D, Smith A, Gonzalez D, Rappaport E, Dunwoodie S, et al
. Cyclical expression of the Notch/Wnt regulator Nrarp requires modulation by Dll3 in somitogenesis. Dev Biol. 2009;329:400-9 pubmed publisher
..Towards identifying the role of Dll3 in regulating somitogenesis, Nrarp emerges as a potentially important regulator that requires Dll3 but not Lfng for normal function...
Iacovelli S, Iosue I, Di Cesare S, Guttinger M. Lymphoid EVA1 expression is required for DN1-DN3 thymocytes transition. PLoS ONE. 2009;4:e7586 pubmed publisher
..We examined the role played by Epithelial V-like Antigen 1 (EVA1), an Ig adhesion molecule expressed on thymus epithelial cells (TEC) and immature thymocytes, in T cell development ..
Wright E, Rahgozar K, Hallworth N, Lanker S, Carrithers M. Epithelial V-like antigen mediates efficacy of anti-alpha? integrin treatment in a mouse model of multiple sclerosis. PLoS ONE. 2013;8:e70954 pubmed publisher
..Here our goal was to analyze the effects of epithelial V-like antigen (EVA) on anti-alpha? integrin (VLA4) efficacy in a mouse model of MS, experimental autoimmune encephalomyelitis (EAE)...
Hooper J, Feng W, Li H, Leach S, Phang T, Siska C, et al
. Systems biology of facial development: contributions of ectoderm and mesenchyme. Dev Biol. 2017;426:97-114 pubmed publisher