Gene Symbol: Mpzl2
Description: myelin protein zero-like 2
Alias: Eva, Eva1, myelin protein zero-like protein 2, epithelial V-like antigen 1
Species: mouse
Products:     Mpzl2

Top Publications

  1. DeMonte L, Porcellini S, Tafi E, Sheridan J, Gordon J, Depreter M, et al. EVA regulates thymic stromal organisation and early thymocyte development. Biochem Biophys Res Commun. 2007;356:334-40 pubmed
    Epithelial V-like antigen (EVA) is an immunoglobulin-like adhesion molecule identified in a screen for molecules developmentally regulated at the DN to DP progression in thymocyte development...
  2. Guttinger M, Sutti F, Panigada M, Porcellini S, Merati B, Mariani M, et al. Epithelial V-like antigen (EVA), a novel member of the immunoglobulin superfamily, expressed in embryonic epithelia with a potential role as homotypic adhesion molecule in thymus histogenesis. J Cell Biol. 1998;141:1061-71 pubmed
    ..identification of a gene encoding a new member of the immunoglobulin superfamily, named epithelial V-like antigen (EVA), which is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression...
  3. Teesalu T, Grassi F, Guttinger M. Expression pattern of the epithelial v-like antigen (Eva) transcript suggests a possible role in placental morphogenesis. Dev Genet. 1998;23:317-23 pubmed
    ..Epithelial V-like Antigen (Eva) is a novel homophilic adhesion molecule of the immunoglobulin superfamily, which during mouse embryonic ..
  4. Chatterjee G, Carrithers L, Carrithers M. Epithelial V-like antigen regulates permeability of the blood-CSF barrier. Biochem Biophys Res Commun. 2008;372:412-7 pubmed publisher
    Epithelial V-like antigen (EVA), a CD3-binding immunoglobulin-like protein, regulates embryonic thymic development...
  5. Sewell W, Sparrow D, Smith A, Gonzalez D, Rappaport E, Dunwoodie S, et al. Cyclical expression of the Notch/Wnt regulator Nrarp requires modulation by Dll3 in somitogenesis. Dev Biol. 2009;329:400-9 pubmed publisher
    ..Towards identifying the role of Dll3 in regulating somitogenesis, Nrarp emerges as a potentially important regulator that requires Dll3 but not Lfng for normal function...
  6. Iacovelli S, Iosue I, Di Cesare S, Guttinger M. Lymphoid EVA1 expression is required for DN1-DN3 thymocytes transition. PLoS ONE. 2009;4:e7586 pubmed publisher
    ..We examined the role played by Epithelial V-like Antigen 1 (EVA1), an Ig adhesion molecule expressed on thymus epithelial cells (TEC) and immature thymocytes, in T cell development ..
  7. Wright E, Rahgozar K, Hallworth N, Lanker S, Carrithers M. Epithelial V-like antigen mediates efficacy of anti-alpha? integrin treatment in a mouse model of multiple sclerosis. PLoS ONE. 2013;8:e70954 pubmed publisher
    ..Here our goal was to analyze the effects of epithelial V-like antigen (EVA) on anti-alpha? integrin (VLA4) efficacy in a mouse model of MS, experimental autoimmune encephalomyelitis (EAE)...
  8. Hooper J, Feng W, Li H, Leach S, Phang T, Siska C, et al. Systems biology of facial development: contributions of ectoderm and mesenchyme. Dev Biol. 2017;426:97-114 pubmed publisher