Gene Symbol: Mir370
Description: microRNA 370
Alias: Mirn370, mmu-mir-370
Qi L, Hongjuan H, Ning G, Zhengbin H, Yanjiang X, Tiebo Z, et al
. miR-370 is stage-specifically expressed during mouse embryonic development and regulates Dnmt3a. FEBS Lett. 2013;587:775-81 pubmed publisher
..Altogether, our results indicate that miR-370 may play important roles in the morphogenesis of diverse organs, especially brain and adrenal glands, by mediating Dnmt3a expression during mouse development. ..
Li L, Li G, Yu C, Shen Z, Xu C, Feng Z, et al
. A role of microRNA-370 in hepatic ischaemia-reperfusion injury by targeting transforming growth factor-? receptor II. Liver Int. 2015;35:1124-32 pubmed publisher
..Our data suggest that miR-370 acting via T?RII might play a potential role in hepatic IR injury, and inhibition of miR-370 efficiently attenuated the damage to the liver. ..
Seitz H, Royo H, Bortolin M, Lin S, Ferguson Smith A, Cavaille J. A large imprinted microRNA gene cluster at the mouse Dlk1-Gtl2 domain. Genome Res. 2004;14:1741-8 pubmed
..The functions of these miRNAs, which seem only conserved in mammals, are discussed both in terms of epigenetic control and gene regulation during development. ..
Iliopoulos D, Drosatos K, Hiyama Y, Goldberg I, Zannis V. MicroRNA-370 controls the expression of microRNA-122 and Cpt1alpha and affects lipid metabolism. J Lipid Res. 2010;51:1513-23 pubmed publisher
Itoh T, Ando M, Tsukamasa Y, Akao Y. Expression of BMP-2 and Ets1 in BMP-2-stimulated mouse pre-osteoblast differentiation is regulated by microRNA-370. FEBS Lett. 2012;586:1693-701 pubmed publisher
..To ascertain the mechanisms underlying the regulation of osteoblast differentiation by miR-370, we hypothesized a BMP-2-Ets1-PTHrP feed-forward loop regulatory mechanism. ..
Benatti R, Melo A, Borges F, Ignacio Souza L, Simino L, Milanski M, et al
. Maternal high-fat diet consumption modulates hepatic lipid metabolism and microRNA-122 (miR-122) and microRNA-370 (miR-370) expression in offspring. Br J Nutr. 2014;111:2112-22 pubmed publisher
Zhang Z, Liu H, Li Q. Glucagon-like peptide-1 effects lipotoxic oxidative stress by regulating the expression of microRNAs. Biochem Biophys Res Commun. 2017;482:1462-1468 pubmed publisher
..These results demonstrated for the first time that GLP-1 improve lipotoxic oxidative stress of pancreas by regulate expression of microRNAs. ..
Zhu J, Zhu F, Song W, Zhang B, Zhang X, Jin X, et al
. Altered miR-370 expression in hepatic ischemia-reperfusion injury correlates with the level of nuclear kappa B (NF-?B) related factors. Gene. 2017;607:23-30 pubmed publisher
..miR-370 acting via NF-?B might play a crucial role in hepatic IR injury, and inhibition of miR-370 could alleviate the injury to the liver. And miR-370 might positively regulated the NF-?B pathway. ..
Feng Y, Wang L, Zeng J, Shen L, Liang X, Yu H, et al
. FoxM1 is overexpressed in Helicobacter pylori-induced gastric carcinogenesis and is negatively regulated by miR-370. Mol Cancer Res. 2013;11:834-44 pubmed publisher
..These findings delineate the mechanisms governing FoxM1 regulation and the role of H. pylori in the process of gastric carcinogenesis. ..