Gene Symbol: Mir367
Description: microRNA 367
Alias: Mirn367, mmu-mir-367
Pernaute B, Spruce T, Smith K, SÃ¡nchez Nieto J, Manzanares M, Cobb B, et al
. MicroRNAs control the apoptotic threshold in primed pluripotent stem cells through regulation of BIM. Genes Dev. 2014;28:1873-8 pubmed publisher
..These families therefore represent an essential buffer needed to maintain cell survival in stem cells that are primed for not only differentiation but also cell death. ..
Tian Y, Zhang Y, Hurd L, Hannenhalli S, Liu F, Lu M, et al
. Regulation of lung endoderm progenitor cell behavior by miR302/367. Development. 2011;138:1235-45 pubmed publisher
..Thus, miR302/367 directs lung endoderm development by coordinating multiple aspects of progenitor cell behavior, including proliferation, differentiation and apical-basal polarity. ..
Zhu Z, Xu Y, Zhao J, Liu Q, Feng W, Fan J, et al
. miR-367 promotes epithelial-to-mesenchymal transition and invasion of pancreatic ductal adenocarcinoma cells by targeting the Smad7-TGF-Î² signalling pathway. Br J Cancer. 2015;112:1367-75 pubmed publisher
..Our results suggest that miR-367 may be a promising therapeutic target for the treatment of human pancreatic cancer. ..
Tian Y, Liu Y, Wang T, Zhou N, Kong J, Chen L, et al
. A microRNA-Hippo pathway that promotes cardiomyocyte proliferation and cardiac regeneration in mice. Sci Transl Med. 2015;7:279ra38 pubmed publisher
..Our data demonstrate the ability of microRNA-based therapeutic approaches to promote mammalian cardiac repair and regeneration through the transient activation of cardiomyocyte proliferation. ..
Parchem R, Moore N, Fish J, Parchem J, Braga T, Shenoy A, et al
. miR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability. Cell Rep. 2015;12:760-73 pubmed publisher
..Our results show that mir-302 helps regulate neurulation by suppressing neural progenitor expansion and precocious differentiation. Furthermore, these results uncover redundant roles for mir-290 and mir-302 early in development. ..