Gene Symbol: M1ap
Description: meiosis 1 associated protein
Alias: D6Mm5e, meiosis 1 arrest protein, meiosis 1-arresting protein, spermatogenesis-associated protein 37
Weber J, Jang W, Simin K, Lu W, Yu J, Meisler M. High-resolution genetic, physical, and transcript map of the mnd2 region of mouse chromosome 6. Genomics. 1998;54:107-15 pubmed
..candidate genes previously mapped to the region and five newly isolated genes is centromere-Hexokinase II-D6Mm5e-p62 Dok-Aup1-Rhotekin, D6Mm3e-Dynactin 1-Smooth muscle gamma actin-D6Mm4e-beta-adducin-telomere...
Jang W, Hua A, Spilson S, Miller W, Roe B, Meisler M. Comparative sequence of human and mouse BAC clones from the mnd2 region of chromosome 2p13. Genome Res. 1999;9:53-61 pubmed
..3. Three genes with the indicated sizes and intergenic distances were identified: D6Mm5e (>/=81 kb)-787 bp-DOK (2 kb)-845 bp-LOR2 (>/=6 kb)...
Arango N, Huang T, Fujino A, Pieretti Vanmarcke R, Donahoe P. Expression analysis and evolutionary conservation of the mouse germ cell-specific D6Mm5e gene. Dev Dyn. 2006;235:2613-9 pubmed
During our search for genes required for gonadal development and function in the mouse, we identified D6Mm5e (DNA segment, Chr 6...
Bird A, Flecknoe S, Tan K, Olsson P, Antony N, Mantamadiotis T, et al
. cAMP response element binding protein is required for differentiation of respiratory epithelium during murine development. PLoS ONE. 2011;6:e17843 pubmed publisher
..Together, these results demonstrate a crucial role for Creb1 activity for the development and differentiation of the conducting and distal lung epithelium. ..
Arango N, Li L, Dabir D, Nicolau F, Pieretti Vanmarcke R, Koehler C, et al
. Meiosis I arrest abnormalities lead to severe oligozoospermia in meiosis 1 arresting protein (M1ap)-deficient mice. Biol Reprod. 2013;88:76 pubmed publisher
b>Meiosis 1 arresting protein (M1ap) is a novel vertebrate gene expressed exclusively in germ cells of the embryonic ovary and the adult testis...