Gene Symbol: Lrrtm4
Description: leucine rich repeat transmembrane neuronal 4
Alias: 7530419J18Rik, A230052N11, leucine-rich repeat transmembrane neuronal protein 4
Species: mouse
Products:     Lrrtm4

Top Publications

  1. Lauren J, Airaksinen M, Saarma M, Timmusk T. A novel gene family encoding leucine-rich repeat transmembrane proteins differentially expressed in the nervous system. Genomics. 2003;81:411-21 pubmed
    ..All LRRTMs, except LRRTM4, are located in the introns of different alpha-catenin genes, suggesting coevolution of these two gene families...
  2. Haines B, Rigby P. Developmentally regulated expression of the LRRTM gene family during mid-gestation mouse embryogenesis. Gene Expr Patterns. 2007;7:23-9 pubmed
    ..Additional expression is seen in the neural tube, forebrain and hindbrain. LRRTM4 is expressed in the limb mesenchyme, neural tube, caudal mesoderm and in three distinct regions of the head...
  3. Schwenk J, Harmel N, Brechet A, Zolles G, Berkefeld H, Müller C, et al. High-resolution proteomics unravel architecture and molecular diversity of native AMPA receptor complexes. Neuron. 2012;74:621-33 pubmed publisher
    ..6 and 1 MDa. The additional constituents change the gating properties of AMPARs and provide links to the protein dynamics fundamental for the complex role of AMPARs in formation and operation of glutamatergic synapses. ..
  4. Siddiqui T, Tari P, Connor S, Zhang P, Dobie F, She K, et al. An LRRTM4-HSPG complex mediates excitatory synapse development on dentate gyrus granule cells. Neuron. 2013;79:680-95 pubmed publisher
    ..We find that LRRTM4 has distinct presynaptic binding partners, heparan sulfate proteoglycans (HSPGs)...