Lrrn3

Summary

Gene Symbol: Lrrn3
Description: leucine rich repeat protein 3, neuronal
Alias: NLRR-3, leucine-rich repeat neuronal protein 3
Species: mouse
Products:     Lrrn3

Top Publications

  1. Aruga J. Slitrk6 expression profile in the mouse embryo and its relationship to that of Nlrr3. Gene Expr Patterns. 2003;3:727-33 pubmed
    ..The complementary expression of the two proteins in the dorsal thalamus persisted from E13.5 to the adult stage. ..
  2. Haines B, Gupta R, Jones C, Summerbell D, Rigby P. The NLRR gene family and mouse development: Modified differential display PCR identifies NLRR-1 as a gene expressed in early somitic myoblasts. Dev Biol. 2005;281:145-59 pubmed
    ..The regulated embryonic expression and cellular location of these proteins suggest important roles during mouse development in the control of cell adhesion, movement or signalling. ..
  3. Taniguchi H, Tohyama M, Takagi T. Cloning and expression of a novel gene for a protein with leucine-rich repeats in the developing mouse nervous system. Brain Res Mol Brain Res. 1996;36:45-52 pubmed
    ..The molecular structure in addition to the transient and localized expression suggests that the NLRR-3 protein plays a role in the development and maintenance of the nervous system by protein-protein interactions. ..
  4. Fukamachi K, Matsuoka Y, Kitanaka C, Kuchino Y, Tsuda H. Rat neuronal leucine-rich repeat protein-3: cloning and regulation of the gene expression. Biochem Biophys Res Commun. 2001;287:257-63 pubmed
    ..LY294002, a PI3 kinase inhibitor, showed a lesser effect on expression of the gene. These results indicate that rNLRR-3 gene expression is regulated mainly through the Ras-MAPK signaling pathway in fibroblasts. ..