Gene Symbol: Lrrc4c
Description: leucine rich repeat containing 4C
Alias: 6430556C10Rik, NGL-1, leucine-rich repeat-containing protein 4C, netrin-G1 ligand
Species: mouse
Products:     Lrrc4c

Top Publications

  1. Lin J, Ho W, Gurney A, Rosenthal A. The netrin-G1 ligand NGL-1 promotes the outgrowth of thalamocortical axons. Nat Neurosci. 2003;6:1270-6 pubmed
    ..Our findings provide evidence that netrin-G1 functions as an important component of the NGL-1 receptor to promote TCA outgrowth and that membrane-bound netrins can participate in receiving axonal signaling pathways. ..
  2. Delprat B, Michel V, Goodyear R, Yamasaki Y, Michalski N, El Amraoui A, et al. Myosin XVa and whirlin, two deafness gene products required for hair bundle growth, are located at the stereocilia tips and interact directly. Hum Mol Genet. 2005;14:401-10 pubmed
    ..The interaction between whirlin and NGL-1 might be involved in the stabilization of interstereociliar links. ..
  3. Kim S, Burette A, Chung H, Kwon S, Woo J, Lee H, et al. NGL family PSD-95-interacting adhesion molecules regulate excitatory synapse formation. Nat Neurosci. 2006;9:1294-301 pubmed
    ..NGL-2 knockdown reduced excitatory, but not inhibitory, synapse numbers and currents. These results suggest that NGL regulates the formation of excitatory synapses. ..
  4. Sturgis S. Editorial: Allan Guttmacher, M.D.--a life fulfilled. N Engl J Med. 1974;290:1085 pubmed
    ..In the 1920s when other doctors were conservatively cautious about the use of IUDs, Guttmacher championed the device, especially for use in underdeveloped countries where other methods were less available or less acceptable. ..
  5. Nishimura Akiyoshi S, Niimi K, Nakashiba T, Itohara S. Axonal netrin-Gs transneuronally determine lamina-specific subdendritic segments. Proc Natl Acad Sci U S A. 2007;104:14801-6 pubmed