Gene Symbol: Lrba
Description: LPS-responsive beige-like anchor
Alias: C80285, D3Ertd775e, Lab300, Lba, lipopolysaccharide-responsive and beige-like anchor protein, beige-like protein
Species: mouse
Products:     Lrba

Top Publications

  1. Tsang W, Shek K, Lee T, Chow K. An evolutionarily conserved nested gene pair - Mab21 and Lrba/Nbea in metazoan. Genomics. 2009;94:177-87 pubmed publisher
    ..genomic sequence comparison strategy was used in this study to align these paralogous nested pairs, Mab21l2-Lrba and Mab21l1-Nbea, to identify the associated paralogous non-coding elements (pNEs) they shared...
  2. Vogl C, Butola T, Haag N, Hausrat T, Leitner M, Moutschen M, et al. The BEACH protein LRBA is required for hair bundle maintenance in cochlear hair cells and for hearing. EMBO Rep. 2017;18:2015-2029 pubmed publisher
    Lipopolysaccharide-responsive beige-like anchor protein (LRBA) belongs to the enigmatic class of BEACH domain-containing proteins, which have been attributed various cellular functions, typically involving intracellular protein and ..
  3. Dyomin V, Chaganti S, Dyomina K, Palanisamy N, Murty V, Dalla Favera R, et al. BCL8 is a novel, evolutionarily conserved human gene family encoding proteins with presumptive protein kinase A anchoring function. Genomics. 2002;80:158-65 pubmed
    ..b>LRBA, a human gene with a ubiquitous expression pattern mapping to 4q32, encodes a protein closely related to BCL8...
  4. Park M, Sudan R, Srivastava N, Neelam S, Youngs C, Wang J, et al. LRBA is Essential for Allogeneic Responses in Bone Marrow Transplantation. Sci Rep. 2016;6:36568 pubmed publisher
    ..LPS-Responsive-Beige-like Anchor (LRBA) is a PBW protein whose immune function remains elusive...
  5. Feng W, Leach S, Tipney H, Phang T, Geraci M, Spritz R, et al. Spatial and temporal analysis of gene expression during growth and fusion of the mouse facial prominences. PLoS ONE. 2009;4:e8066 pubmed publisher
    ..Overall, our studies provide a valuable resource for probing orofacial development and a robust dataset for bioinformatic analysis of spatial and temporal gene expression changes during embryogenesis. ..
  6. Kurtenbach S, Gießl A, Strömberg S, Kremers J, Atorf J, Rasche S, et al. The BEACH Protein LRBA Promotes the Localization of the Heterotrimeric G-protein Golf to Olfactory Cilia. Sci Rep. 2017;7:8409 pubmed publisher
    ..The BEACH protein LRBA has been implicated in immune response and cell proliferation, and human LRBA mutations cause severe immune ..
  7. Wang J, Howson J, Haller E, Kerr W. Identification of a novel lipopolysaccharide-inducible gene with key features of both A kinase anchor proteins and chs1/beige proteins. J Immunol. 2001;166:4586-95 pubmed
    ..We designate this novel gene lba for LPS-responsive, beige-like anchor gene...
  8. Medrihan L, Rohlmann A, Fairless R, Andrae J, Döring M, Missler M, et al. Neurobeachin, a protein implicated in membrane protein traffic and autism, is required for the formation and functioning of central synapses. J Physiol. 2009;587:5095-106 pubmed publisher