Genomes and Genes
Gene Symbol: Lnpk
Description: lunapark, ER junction formation factor
Alias: 2310011O18Rik, 4921514L11Rik, 9530051D01Rik, AI666268, Lnp, Lnpk1, ulnaless, endoplasmic reticulum junction formation protein lunapark, protein lunapark, ER junction formation factor 1, ER junction formation factor lunapark, limb and neural patterns, protein ulnaless
- Montavon T, Thevenet L, Duboule D. Impact of copy number variations (CNVs) on long-range gene regulation at the HoxD locus. Proc Natl Acad Sci U S A. 2012;109:20204-11 pubmed publisher..These results illustrate the detrimental consequences of interrupting highly conserved regulatory landscapes and reveal a mechanism where genomic duplications lead to partial loss of function of nearby located genes. ..
- Montavon T, Le Garrec J, Kerszberg M, Duboule D. Modeling Hox gene regulation in digits: reverse collinearity and the molecular origin of thumbness. Genes Dev. 2008;22:346-59 pubmed publisher..We also show that the same model applies to the collinear regulation of Hox genes during the emergence of external genitalia, though with some differences likely illustrating the distinct functionalities of these structures in adults. ..
- Delpretti S, Montavon T, Leleu M, Joye E, Tzika A, Milinkovitch M, et al. Multiple enhancers regulate Hoxd genes and the Hotdog LncRNA during cecum budding. Cell Rep. 2013;5:137-50 pubmed publisher..In this context, we discuss the implementation of a common "budding toolkit" between the cecum and the limbs. ..