Gene Symbol: Kif14
Description: kinesin family member 14
Alias: D1Ertd367e, E130203M01, kinesin-like protein KIF14, N-3 kinesin, truncated kinesin family member 14
Yunus J, Setsu T, Kikkawa S, Sakisaka T, Terashima T. Cytoarchitecture of the olfactory bulb in the laggard mutant mouse. Neuroscience. 2014;275:259-71 pubmed publisher
..by hypomyelination and cerebellar ataxia, is a spontaneously occurring mutant mouse caused by mutation in the Kif14 gene...
Arora K, Talje L, Asenjo A, Andersen P, Atchia K, Joshi M, et al
. KIF14 binds tightly to microtubules and adopts a rigor-like conformation. J Mol Biol. 2014;426:2997-3015 pubmed publisher
The mitotic kinesin motor protein KIF14 is essential for cytokinesis during cell division and has been implicated in cerebral development and a variety of human cancers...
Winter H, Siry P, Tobiasch E, Schweizer J. Sequence and expression of murine type I hair keratins mHa2 and mHa3. Exp Cell Res. 1994;212:190-200 pubmed
..These data indicate that the structural heterogeneity within the type I hair keratin subfamily is functionally relevant in the morphogenesis of hard alpha-keratin-expressing tissues. ..
Pajovic S, Corson T, Spencer C, Dimaras H, Orlic Milacic M, Marchong M, et al
. The TAg-RB murine retinoblastoma cell of origin has immunohistochemical features of differentiated Muller glia with progenitor properties. Invest Ophthalmol Vis Sci. 2011;52:7618-24 pubmed publisher
..Here, the characteristics of the TAg-RB cell of origin are defined...
Fujikura K, Setsu T, Tanigaki K, Abe T, Kiyonari H, Terashima T, et al
. Kif14 mutation causes severe brain malformation and hypomyelination. PLoS ONE. 2013;8:e53490 pubmed publisher
..By positional cloning, we identify a splice site mutation in Kif14. Transgenic complementation with wild-type Kif14-cDNA alleviates ataxic phenotype in lag/lag mice...
Schultz N, Ingels J, Hillhouse A, Wardwell K, Chang P, Cheverud J, et al
. The Genetic Basis of Baculum Size and Shape Variation in Mice. G3 (Bethesda). 2016;6:1141-51 pubmed publisher
O Hare M, Shadmand M, Sulaiman R, Sishtla K, Sakisaka T, Corson T. Kif14 overexpression accelerates murine retinoblastoma development. Int J Cancer. 2016;139:1752-8 pubmed publisher
The mitotic kinesin KIF14 has an essential role in the recruitment of proteins required for the final stages of cytokinesis...