Kif14

Summary

Gene Symbol: Kif14
Description: kinesin family member 14
Alias: D1Ertd367e, E130203M01, kinesin-like protein KIF14, N-3 kinesin, truncated kinesin family member 14
Species: mouse
Products:     Kif14

Top Publications

  1. Yunus J, Setsu T, Kikkawa S, Sakisaka T, Terashima T. Cytoarchitecture of the olfactory bulb in the laggard mutant mouse. Neuroscience. 2014;275:259-71 pubmed publisher
    ..by hypomyelination and cerebellar ataxia, is a spontaneously occurring mutant mouse caused by mutation in the Kif14 gene...
  2. Arora K, Talje L, Asenjo A, Andersen P, Atchia K, Joshi M, et al. KIF14 binds tightly to microtubules and adopts a rigor-like conformation. J Mol Biol. 2014;426:2997-3015 pubmed publisher
    The mitotic kinesin motor protein KIF14 is essential for cytokinesis during cell division and has been implicated in cerebral development and a variety of human cancers...
  3. Winter H, Siry P, Tobiasch E, Schweizer J. Sequence and expression of murine type I hair keratins mHa2 and mHa3. Exp Cell Res. 1994;212:190-200 pubmed
    ..These data indicate that the structural heterogeneity within the type I hair keratin subfamily is functionally relevant in the morphogenesis of hard alpha-keratin-expressing tissues. ..
  4. Pajovic S, Corson T, Spencer C, Dimaras H, Orlic Milacic M, Marchong M, et al. The TAg-RB murine retinoblastoma cell of origin has immunohistochemical features of differentiated Muller glia with progenitor properties. Invest Ophthalmol Vis Sci. 2011;52:7618-24 pubmed publisher
    ..Here, the characteristics of the TAg-RB cell of origin are defined...
  5. Fujikura K, Setsu T, Tanigaki K, Abe T, Kiyonari H, Terashima T, et al. Kif14 mutation causes severe brain malformation and hypomyelination. PLoS ONE. 2013;8:e53490 pubmed publisher
    ..By positional cloning, we identify a splice site mutation in Kif14. Transgenic complementation with wild-type Kif14-cDNA alleviates ataxic phenotype in lag/lag mice...
  6. Schultz N, Ingels J, Hillhouse A, Wardwell K, Chang P, Cheverud J, et al. The Genetic Basis of Baculum Size and Shape Variation in Mice. G3 (Bethesda). 2016;6:1141-51 pubmed publisher
  7. O Hare M, Shadmand M, Sulaiman R, Sishtla K, Sakisaka T, Corson T. Kif14 overexpression accelerates murine retinoblastoma development. Int J Cancer. 2016;139:1752-8 pubmed publisher
    The mitotic kinesin KIF14 has an essential role in the recruitment of proteins required for the final stages of cytokinesis...