Kat14

Summary

Gene Symbol: Kat14
Description: lysine acetyltransferase 14
Alias: 2510008M08Rik, ATAC2, AU023459, Csrp2bp, D2Ertd473e, D2Wsu131e, E430020F17, cysteine-rich protein 2-binding protein, ADA2A-containing complex subunit 2, CRP2-binding partner, CRP2BP, CSRP2-binding protein, cysteine and glycine-rich protein 2 binding protein
Species: mouse
Products:     Kat14

Top Publications

  1. Guelman S, Kozuka K, Mao Y, Pham V, Solloway M, Wang J, et al. The double-histone-acetyltransferase complex ATAC is essential for mammalian development. Mol Cell Biol. 2009;29:1176-88 pubmed publisher
    ..report the characterization of a novel mammalian HAT complex, which contains the two acetyltransferases GCN5 and ATAC2 as well as other proteins linked to chromatin metabolism...
  2. Orpinell M, Fournier M, Riss A, Nagy Z, Krebs A, Frontini M, et al. The ATAC acetyl transferase complex controls mitotic progression by targeting non-histone substrates. EMBO J. 2010;29:2381-94 pubmed publisher
    ..Thus, we have uncovered an essential function for ATAC in regulating Cyclin A activity and consequent mitotic progression. ..
  3. Shen A, O Leary K, Dubielzig R, Drinkwater N, Murphy C, Kasper C, et al. The PPCD1 mouse: characterization of a mouse model for posterior polymorphous corneal dystrophy and identification of a candidate gene. PLoS ONE. 2010;5:e12213 pubmed publisher
    ..The endpoints of the duplication are located in positions that disrupt the genes Csrp2bp and 6330439K17Rik and lead to duplication of the pseudogene LOC100043552...
  4. Shen A, Moran S, Glover E, Drinkwater N, Swearingen R, Teixeira L, et al. Association of a Chromosomal Rearrangement Event with Mouse Posterior Polymorphous Corneal Dystrophy and Alterations in Csrp2bp, Dzank1, and Ovol2 Gene Expression. PLoS ONE. 2016;11:e0157577 pubmed publisher
    ..9 Mbp chromosomal inversion flanked by 81 Kbp and 542 bp deletions. This recombination event leads to deletion of Csrp2bp Exons 8 through 11, Dzank1 Exons 20 and 21, and the pseudogene Znf133...
  5. Ma Y, Li Q, Li A, Wei Y, Long P, Jiang X, et al. The CSRP2BP histone acetyltransferase drives smooth muscle gene expression. Nucleic Acids Res. 2017;45:3046-3058 pubmed publisher
    ..Here, we report that CSRP2BP, a coactivator for CRP2, is a histone acetyltransferase and a driver of smooth muscle gene expression...