Genomes and Genes
Gene Symbol: Itga11
Description: integrin alpha 11
Alias: 4732459H24Rik, integrin alpha-11, integrin a11
- Leomil Coelho L, Mota B, Sales P, Marques J, de Oliveira J, Bonjardim C, et al. Integrin alpha 11 is a novel type I interferon stimulated gene. Cytokine. 2006;33:352-61 pubmed..The aim of this work was to investigate whether integrin alpha 11 (ITGA-11), a novel collagen-binding integrin, is responsive to type I IFN treatment...
- Popova S, Barczyk M, Tiger C, Beertsen W, Zigrino P, Aszodi A, et al. Alpha11 beta1 integrin-dependent regulation of periodontal ligament function in the erupting mouse incisor. Mol Cell Biol. 2007;27:4306-16 pubmed..Our data show a unique role for alpha11beta1 integrin during tooth eruption. ..
- Caswell C, Barczyk M, Keene D, Lukomska E, Gullberg D, Lukomski S. Identification of the first prokaryotic collagen sequence motif that mediates binding to human collagen receptors, integrins alpha2beta1 and alpha11beta1. J Biol Chem. 2008;283:36168-75 pubmed publisher..This work is a stepping stone toward defining the utilization of collagen receptors by microbial collagen-like proteins that are expressed by pathogenic bacteria. ..
- Svendsen Ø, Barczyk M, Popova S, Liden A, Gullberg D, Wiig H. The alpha11beta1 integrin has a mechanistic role in control of interstitial fluid pressure and edema formation in inflammation. Arterioscler Thromb Vasc Biol. 2009;29:1864-70 pubmed publisher..Our data suggest that alpha11beta1 integrins on dermal fibroblasts mediate collagen lattice remodeling and have a mechanistic role in controlling Pif in inflammation and thereby fluid extravasation and edema formation in vivo. ..
- Gouttenoire J, Bougault C, Aubert Foucher E, Perrier E, Ronzière M, Sandell L, et al. BMP-2 and TGF-beta1 differentially control expression of type II procollagen and alpha 10 and alpha 11 integrins in mouse chondrocytes. Eur J Cell Biol. 2010;89:307-14 pubmed publisher..This result strongly suggests that signaling pathways other than Smad proteins are involved in the effect of BMP-2 on type II procollagen expression. ..
- Reigstad I, Smeland H, Skogstrand T, Sortland K, Schmid M, Reed R, et al. Stromal Integrin ?11?1 Affects RM11 Prostate and 4T1 Breast Xenograft Tumors Differently. PLoS ONE. 2016;11:e0151663 pubmed publisher..Deficiency of stromal integrin ?11?1 showed different effects on tumor growth and collagen fibril diameter depending on tumor type, but no effect on tumor PIF or development of lung metastasis. ..