Ispd

Summary

Gene Symbol: Ispd
Description: isoprenoid synthase domain containing
Alias: 4930579E17Rik, AV040780, D-ribitol-5-phosphate cytidylyltransferase, isoprenoid synthase domain-containing protein, 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase-like protein, notch1-induced protein
Species: mouse
Products:     Ispd

Top Publications

  1. Wright K, Lyon K, Leung H, Leahy D, Ma L, Ginty D. Dystroglycan organizes axon guidance cue localization and axonal pathfinding. Neuron. 2012;76:931-44 pubmed publisher
    ..Using a murine forward genetic screen for novel determinants of axon guidance, we identified B3gnt1 and ISPD as required for the glycosylation of dystroglycan in vivo...
  2. Rakowski L, Garagiola D, Li C, Decker M, Caruso S, Jones M, et al. Convergence of the ZMIZ1 and NOTCH1 pathways at C-MYC in acute T lymphoblastic leukemias. Cancer Res. 2013;73:930-41 pubmed publisher
    ..They also raise new inquiries into potential NOTCH-ZMIZ1 collaboration in a variety of C-MYC-driven cancers. ..
  3. Yagi H, Nakagawa N, Saito T, Kiyonari H, Abe T, Toda T, et al. AGO61-dependent GlcNAc modification primes the formation of functional glycans on ?-dystroglycan. Sci Rep. 2013;3:3288 pubmed publisher
    ..These findings provide a key missing link for understanding how the physiologically critical glycan motif is displayed on ?-DG and provides new insights on the pathological mechanisms of dystroglycanopathy. ..
  4. Lee A, Lloyd K. Conditional targeting of Ispd using paired Cas9 nickase and a single DNA template in mice. FEBS Open Bio. 2014;4:637-42 pubmed publisher
    ..single DNA template encoding two loxP sites flanking (floxing) exon 2 of the isoprenoid synthase containing domain (Ispd) into the pronucleus and cytoplasm of C57BL/6NCr one-cell stage zygotes...