Igflr1

Summary

Gene Symbol: Igflr1
Description: IGF-like family receptor 1
Alias: F630003I17Rik, Tmem149, IGF-like family receptor 1, U2 small nuclear RNA auxiliary factor 1-like 4, transmembrane protein 149
Species: mouse
Products:     Igflr1

Top Publications

  1. Shepard J, Reick M, Olson S, Graveley B. Characterization of U2AF(6), a splicing factor related to U2AF(35). Mol Cell Biol. 2002;22:221-30 pubmed
    ..Based on its sequence and functional similarity to U2AF(35), U2AF(26) may play a role in regulating alternative splicing. ..
  2. Heyd F, Ten Dam G, Moroy T. Auxiliary splice factor U2AF26 and transcription factor Gfi1 cooperate directly in regulating CD45 alternative splicing. Nat Immunol. 2006;7:859-67 pubmed
    ..We propose that the relative abundance of U2AF26 and Gfi1 determines the ratio of CD45 isoforms, thereby regulating T cell activation. ..
  3. Lobito A, Ramani S, Tom I, Bazan J, Luis E, Fairbrother W, et al. Murine insulin growth factor-like (IGFL) and human IGFL1 proteins are induced in inflammatory skin conditions and bind to a novel tumor necrosis factor receptor family member, IGFLR1. J Biol Chem. 2011;286:18969-81 pubmed publisher
    ..and transmembrane protein library, we discovered high affinity interactions between human IGFL1 and mIGFL and the TMEM149 ectodomain...