Genomes and Genes
Gene Symbol: Ifitm1
Description: interferon induced transmembrane protein 1
Alias: 1110036C17Rik, DSPA2a, Mil-2, Mil2, interferon-induced transmembrane protein 1, dispanin subfamily A member 2a, fragilis protein 2, fragilis2, ifitm-like protein 2, interferon induced transmembrane protein 2 like
- Hach J, McMichael T, Chesarino N, Yount J. Palmitoylation on conserved and nonconserved cysteines of murine IFITM1 regulates its stability and anti-influenza A virus activity. J Virol. 2013;87:9923-7 pubmed publisher..Here, we report that murine IFITM1 (mIFITM1) is palmitoylated on one nonconserved cysteine and three conserved cysteines that are required for anti-..
- Yu M, Qi W, Huang Z, Zhang K, Ye J, Liu R, et al. Expression profile and histological distribution of IFITM1 and IFITM3 during H9N2 avian influenza virus infection in BALB/c mice. Med Microbiol Immunol. 2015;204:505-14 pubmed publisher..Here, we investigated the expression patterns and tissue distribution of IFITM1 and IFITM3 in BALB/c mice by infection with H9N2 AIV strains with only a PB2 residue 627 difference...
- Wee Y, Weis J, Gahring L, Rogers S, Weis J. Age-related onset of obesity corresponds with metabolic dysregulation and altered microglia morphology in mice deficient for Ifitm proteins. PLoS ONE. 2015;10:e0123218 pubmed publisher..Further, this novel phenotype for the IfitmDel mouse could be related to abnormal neuropeptide production, inflammatory status and microglia status in the hypothalamus. ..
- Sun J, Ting M, Ishii M, Maxson R. Msx1 and Msx2 function together in the regulation of primordial germ cell migration in the mouse. Dev Biol. 2016;417:11-24 pubmed publisher..We also noted a reduction in the expression of Wnt5a and an increase in the expression in Bmp4 in such tissues in Msx1(-/-);Msx2(-/-) mutants, both known effectors of PGC development. ..
- Jia R, Ding S, Pan Q, Liu S, Qiao W, Liang C. The C-terminal sequence of IFITM1 regulates its anti-HIV-1 activity. PLoS ONE. 2015;10:e0118794 pubmed publisher..We previously reported the inhibition of human immunodeficiency virus type 1 (HIV-1) strain BH10 by human IFITM1, 2 and 3...