Ido2

Summary

Gene Symbol: Ido2
Description: indoleamine 2,3-dioxygenase 2
Alias: AI265623, C230043N17Rik, Ido-2, Indol1, indoleamine 2,3-dioxygenase-like protein 1, indoleamine-pyrrole 2,3 dioxygenase-like 1
Species: mouse

Top Publications

  1. ncbi Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan
    Richard Metz
    Lankenau Institute for Medical Research, Wynnewood, Pennsylvania 19096, USA
    Cancer Res 67:7082-7. 2007
  2. ncbi Characterization of an indoleamine 2,3-dioxygenase-like protein found in humans and mice
    Helen J Ball
    Discipline of Pathology and Bosch Institute, University of Sydney, NSW 2006, Australia
    Gene 396:203-13. 2007
  3. doi Indoleamine 2,3-dioxygenase-2; a new enzyme in the kynurenine pathway
    Helen J Ball
    Discipline of Pathology and Bosch Institute, University of Sydney, Camperdown, NSW 2006, Australia
    Int J Biochem Cell Biol 41:467-71. 2009
  4. doi Indoleamine 2,3-dioxygenase in T-cell tolerance and tumoral immune escape
    Jessica B Katz
    Lankenau Institute for Medical Research, Wynnewood, PA 19096, USA
    Immunol Rev 222:206-21. 2008
  5. pmc Opposing biological functions of tryptophan catabolizing enzymes during intracellular infection
    Senad Divanovic
    Division of Molecular Immunology, Cincinnati Children s Hospital Research Foundation, and the University of Cincinnati College of Medicine, Ohio, USA
    J Infect Dis 205:152-61. 2012
  6. pmc Studies on tissue and cellular distribution of indoleamine 2,3-dioxygenase 2: the absence of IDO1 upregulates IDO2 expression in the epididymis
    Masakazu Fukunaga
    Human Health Sciences, Graduate School of Medicine and Faculty of Medicine, Kyoto University, Japan
    J Histochem Cytochem 60:854-60. 2012

Scientific Experts

  • Helen J Ball
  • George C Prendergast
  • Senad Divanovic
  • Masakazu Fukunaga
  • James B DuHadaway
  • Silvia Weiser
  • Christopher J D Austin
  • Nicholas H Hunt
  • Jessica B Katz
  • Alexander J Muller
  • Richard Metz
  • Masato Hoshi
  • Nancy M Sawtell
  • Aurelien Trompette
  • Julio Aliberti
  • Christopher L Karp
  • Jamie I Warning
  • Andrew L Mellor
  • Yasuko Yamamoto
  • Randall J Basaraba
  • Kenichi Shimada
  • Kuniaki Saito
  • David H Munn
  • Misaki Kawasoe
  • Alexandra Dias
  • Yuki Murakami
  • Andrea M Cooper
  • George S Yap
  • Moshe Arditi
  • Yuko Arioka
  • Hajime J Yuasa
  • Angeles Sanchez-Perez
  • Jenny Miu
  • James A McQuillan
  • Roland Stocker
  • Lars S Jermiin
  • Uma Kamasani
  • Lisa Laury-Kleintop
  • Florian Astelbauer

Detail Information

Publications6

  1. ncbi Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan
    Richard Metz
    Lankenau Institute for Medical Research, Wynnewood, Pennsylvania 19096, USA
    Cancer Res 67:7082-7. 2007
    ..Here, we report the discovery of a novel IDO-related tryptophan catabolic enzyme termed IDO2 that is preferentially inhibited by D-1MT...
  2. ncbi Characterization of an indoleamine 2,3-dioxygenase-like protein found in humans and mice
    Helen J Ball
    Discipline of Pathology and Bosch Institute, University of Sydney, NSW 2006, Australia
    Gene 396:203-13. 2007
    ..We describe the discovery of another enzyme with this activity, indoleamine 2,3-dioxygenase-like protein (INDOL1), which is closely related to INDO and is expressed in mice and humans...
  3. doi Indoleamine 2,3-dioxygenase-2; a new enzyme in the kynurenine pathway
    Helen J Ball
    Discipline of Pathology and Bosch Institute, University of Sydney, Camperdown, NSW 2006, Australia
    Int J Biochem Cell Biol 41:467-71. 2009
    ..2,3-dioxygenase-2, indoleamine 2,3-dioxygenase-like protein or proto-indoleamine 2,3-dioxygenase (IDO2, IDO-2, INDOL1 or proto-IDO), with this activity recently has been described...
  4. doi Indoleamine 2,3-dioxygenase in T-cell tolerance and tumoral immune escape
    Jessica B Katz
    Lankenau Institute for Medical Research, Wynnewood, PA 19096, USA
    Immunol Rev 222:206-21. 2008
    ....
  5. pmc Opposing biological functions of tryptophan catabolizing enzymes during intracellular infection
    Senad Divanovic
    Division of Molecular Immunology, Cincinnati Children s Hospital Research Foundation, and the University of Cincinnati College of Medicine, Ohio, USA
    J Infect Dis 205:152-61. 2012
    ..Thus, IDO plays biologically important roles in the host response to diverse intracellular infections, but the dominant nature of this role--antimicrobial or immunoregulatory--is pathogen-specific...
  6. pmc Studies on tissue and cellular distribution of indoleamine 2,3-dioxygenase 2: the absence of IDO1 upregulates IDO2 expression in the epididymis
    Masakazu Fukunaga
    Human Health Sciences, Graduate School of Medicine and Faculty of Medicine, Kyoto University, Japan
    J Histochem Cytochem 60:854-60. 2012
    ..Recently, in addition to IDO1, a new isoform called IDO2 was identified...