Ido2

Summary

Gene Symbol: Ido2
Description: indoleamine 2,3-dioxygenase 2
Alias: AI265623, C230043N17Rik, Ido-2, Indol1, indoleamine 2,3-dioxygenase-like protein 1, indoleamine-pyrrole 2,3 dioxygenase-like 1
Species: mouse

Top Publications

  1. ncbi Characterization of an indoleamine 2,3-dioxygenase-like protein found in humans and mice
    Helen J Ball
    Discipline of Pathology and Bosch Institute, University of Sydney, NSW 2006, Australia
    Gene 396:203-13. 2007
  2. ncbi Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan
    Richard Metz
    Lankenau Institute for Medical Research, Wynnewood, Pennsylvania 19096, USA
    Cancer Res 67:7082-7. 2007
  3. doi Indoleamine 2,3-dioxygenase-2; a new enzyme in the kynurenine pathway
    Helen J Ball
    Discipline of Pathology and Bosch Institute, University of Sydney, Camperdown, NSW 2006, Australia
    Int J Biochem Cell Biol 41:467-71. 2009
  4. doi Indoleamine 2,3-dioxygenase in T-cell tolerance and tumoral immune escape
    Jessica B Katz
    Lankenau Institute for Medical Research, Wynnewood, PA 19096, USA
    Immunol Rev 222:206-21. 2008
  5. pmc Opposing biological functions of tryptophan catabolizing enzymes during intracellular infection
    Senad Divanovic
    Division of Molecular Immunology, Cincinnati Children s Hospital Research Foundation, and the University of Cincinnati College of Medicine, Ohio, USA
    J Infect Dis 205:152-61. 2012
  6. pmc Studies on tissue and cellular distribution of indoleamine 2,3-dioxygenase 2: the absence of IDO1 upregulates IDO2 expression in the epididymis
    Masakazu Fukunaga
    Human Health Sciences, Graduate School of Medicine and Faculty of Medicine, Kyoto University, Japan
    J Histochem Cytochem 60:854-60. 2012

Scientific Experts

  • Helen J Ball
  • George C Prendergast
  • Masakazu Fukunaga
  • Senad Divanovic
  • James B DuHadaway
  • Christopher J D Austin
  • Silvia Weiser
  • Jessica B Katz
  • Nicholas H Hunt
  • Alexander J Muller
  • Richard Metz
  • Julio Aliberti
  • Christopher L Karp
  • Moshe Arditi
  • Andrea M Cooper
  • Aurelien Trompette
  • Yuki Murakami
  • Jamie I Warning
  • Misaki Kawasoe
  • Kenichi Shimada
  • Yasuko Yamamoto
  • Andrew L Mellor
  • David H Munn
  • Randall J Basaraba
  • Alexandra Dias
  • Masato Hoshi
  • Nancy M Sawtell
  • Yuko Arioka
  • George S Yap
  • Kuniaki Saito
  • Hajime J Yuasa
  • James A McQuillan
  • Uma Kamasani
  • Jenny Miu
  • Lars S Jermiin
  • Angeles Sanchez-Perez
  • Florian Astelbauer
  • Lisa Laury-Kleintop
  • Roland Stocker

Detail Information

Publications6

  1. ncbi Characterization of an indoleamine 2,3-dioxygenase-like protein found in humans and mice
    Helen J Ball
    Discipline of Pathology and Bosch Institute, University of Sydney, NSW 2006, Australia
    Gene 396:203-13. 2007
    ..We describe the discovery of another enzyme with this activity, indoleamine 2,3-dioxygenase-like protein (INDOL1), which is closely related to INDO and is expressed in mice and humans...
  2. ncbi Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan
    Richard Metz
    Lankenau Institute for Medical Research, Wynnewood, Pennsylvania 19096, USA
    Cancer Res 67:7082-7. 2007
    ..Here, we report the discovery of a novel IDO-related tryptophan catabolic enzyme termed IDO2 that is preferentially inhibited by D-1MT...
  3. doi Indoleamine 2,3-dioxygenase-2; a new enzyme in the kynurenine pathway
    Helen J Ball
    Discipline of Pathology and Bosch Institute, University of Sydney, Camperdown, NSW 2006, Australia
    Int J Biochem Cell Biol 41:467-71. 2009
    ..2,3-dioxygenase-2, indoleamine 2,3-dioxygenase-like protein or proto-indoleamine 2,3-dioxygenase (IDO2, IDO-2, INDOL1 or proto-IDO), with this activity recently has been described...
  4. doi Indoleamine 2,3-dioxygenase in T-cell tolerance and tumoral immune escape
    Jessica B Katz
    Lankenau Institute for Medical Research, Wynnewood, PA 19096, USA
    Immunol Rev 222:206-21. 2008
    ....
  5. pmc Opposing biological functions of tryptophan catabolizing enzymes during intracellular infection
    Senad Divanovic
    Division of Molecular Immunology, Cincinnati Children s Hospital Research Foundation, and the University of Cincinnati College of Medicine, Ohio, USA
    J Infect Dis 205:152-61. 2012
    ..Thus, IDO plays biologically important roles in the host response to diverse intracellular infections, but the dominant nature of this role--antimicrobial or immunoregulatory--is pathogen-specific...
  6. pmc Studies on tissue and cellular distribution of indoleamine 2,3-dioxygenase 2: the absence of IDO1 upregulates IDO2 expression in the epididymis
    Masakazu Fukunaga
    Human Health Sciences, Graduate School of Medicine and Faculty of Medicine, Kyoto University, Japan
    J Histochem Cytochem 60:854-60. 2012
    ..Recently, in addition to IDO1, a new isoform called IDO2 was identified...